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http://krishi.icar.gov.in/jspui/handle/123456789/34538| Title: | Chemo-profiling and bioassay of phytoextracts from Ageratum conyzoides for acaricidal properties against Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) infesting cattle and buffaloes in India |
| Other Titles: | Not Available |
| Authors: | KG Ajith Kumar Amol B Tayade Rajesh Kumar Suman Gupta Anil Kumar Sharma Gaurav Nagar Shashi Shankar Tewari Bhanu Kumar AKS Rawat Sharad Srivastava Sachin Kumar Srikant Ghosh |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::Indian Veterinary Research Institute ICAR::Indian Agricultural Research Institute Division of Pharmacognosy & Ethnopharmacology Division, National Botanical Research Institute, Lucknow 226001, India |
| Published/ Complete Date: | 2016-03-01 |
| Project Code: | Not Available |
| Keywords: | Ageratum conyzoides Chemo-profiling Acaricide resistance Anti-tick activity Chemo-profiling GC/MS/MSRhipicephalus (Boophilus) microplus |
| Publisher: | Not Available |
| Citation: | Not Available |
| Series/Report no.: | Not Available; |
| Abstract/Description: | In India, Rhipicephalus (Boophilus) microplus populations have developed a certain level of resistance to most of the acaricides marketed against tick species. To manage the problem, the present study was undertaken to evaluate the acaricidal potential of Ageratum conyzoides plants against acaricides-resistant ticks infesting cattle and buffaloes. The regression analysis of dose-response data of ethanolic extract of A. conyzoides revealed LC90 value of 8.91% against reference susceptible IVRI-1 line of R.(B.) microplus. The ethanolic extract was found efficacious against 76.7–90% acaricides-resistant field ticks and adversely affected oviposition showing 7.04–31.3% reduction in egg laying capacity. The extract was also showed an in vitro efficacy of 52.5 and 76.7% against reference resistant IVRI-4 and 5 lines. The GC/MS/MS profiling of hexane extract, two bioactive sub-fractions and essential oils revealed the presence of 6,7-dimethoxy-2,2-dimethyl-2H-1-benzopyran (precocene II) as a major phyto-compound. The bioactive sub-fractions showed 96.2–97.5% efficacy against larvae of IVRI-1 and 77.1–94.9% against multi-acaricide resistant larvae of IVRI-5 line of R.(B.) microplus. The results of this study provided significant support for the development of a phyto-formulation based on A. conyzoides species. |
| Description: | Not Available |
| ISSN: | Not Available |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Ticks and tick-borne diseases |
| NAAS Rating: | 8.75 |
| Volume No.: | 7(2) |
| Page Number: | 342-349 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | https://doi.org/10.1016/j.ttbdis.2015.12.005 https://www.sciencedirect.com/science/article/abs/pii/S1877959X15300479?via%3Dihub |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/34538 |
| Appears in Collections: | CS-IARI-Publication |
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