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http://krishi.icar.gov.in/jspui/handle/123456789/46566Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hiremath J | en_US |
| dc.contributor.author | Renu S | en_US |
| dc.contributor.author | Tabynov K | en_US |
| dc.contributor.author | Renukaradhya GJ | en_US |
| dc.date.accessioned | 2021-04-22T03:56:22Z | - |
| dc.date.available | 2021-04-22T03:56:22Z | - |
| dc.date.issued | 2020-02-21 | - |
| dc.identifier.citation | Hiremath J, Renu S, Tabynov K and Renukaradhya GJ. (2020). Pulmonary inflammatory response to influenza virus infection in pigs is regulated by DAP12 and macrophage M1 and M2 phenotypes. Cellular Immunology. 352: 104078. 1-7. Jun; 352:104078. doi: 10.1016/j.cellimm.2020.104078. Epub 2020 Feb 21. PMID: 32164997. | en_US |
| dc.identifier.issn | 0008-8749 | - |
| dc.identifier.uri | http://krishi.icar.gov.in/jspui/handle/123456789/46566 | - |
| dc.description | Not Available | en_US |
| dc.description.abstract | We delineated the expression of DAP12 (DNAX-Activating Protein) and its associated receptors, TREM-1, TREM-2 and MDL-1 in pig alveolar monocyte/macrophages (AMM) that have attained M1 or M2 phenotypes. Pig AMM stimulated in vitro with IFN-γ and IL-4 induced the expression of M1 (TNFα and iNOS) and M2 (ARG1 and no MMR) phenotypic markers, respectively. In influenza virus infected pigs at seven days post-infection, in addition to substantial modulations in the M1 and M2 markers expression, DAP12, TREM-1 and MDL-1 were downregulated in AMM. Thus, DAP12 signaling promoted the anti-inflammatory pathway in AMM of influenza virus infected pigs. | en_US |
| dc.description.sponsorship | Not Available | en_US |
| dc.language.iso | English | en_US |
| dc.publisher | Elsevier Publishers private limited | en_US |
| dc.relation.ispartofseries | Not Available; | - |
| dc.subject | Influenza A virus | en_US |
| dc.subject | DAP12 | en_US |
| dc.subject | M1 and M2 macrophages | en_US |
| dc.subject | Pigs | en_US |
| dc.title | Pulmonary inflammatory response to influenza virus infection in pigs is regulated by DAP12 and macrophage M1 and M2 phenotypes | en_US |
| dc.title.alternative | Not Available | en_US |
| dc.type | Research Paper | en_US |
| dc.publication.projectcode | Not Available | en_US |
| dc.publication.journalname | Cellular Immunology | en_US |
| dc.publication.volumeno | 352(2020) | en_US |
| dc.publication.pagenumber | 1-7 | en_US |
| dc.publication.divisionUnit | Not Available | en_US |
| dc.publication.sourceUrl | https://www.sciencedirect.com/science/article/pii/S0008874919304897 | en_US |
| dc.publication.authorAffiliation | Food Animal Health Research Program, College of Food, Agricultural and Environmental Sciences, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH, USA | en_US |
| dc.publication.authorAffiliation | Kazakh National Agrarian University, Almaty 050010, Kazakhstan and Research Institute of Cardiology and Internal Medicine, Almaty 050000, Kazakhstan | en_US |
| dc.publication.authorAffiliation | ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Bengaluru, Karnataka, India | en_US |
| dc.ICARdataUseLicence | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf | en_US |
| dc.publication.journaltype | International Journal | en_US |
| dc.publication.naasrating | 10.08 | en_US |
| dc.publication.impactfactor | 4.078 | en_US |
| Appears in Collections: | AS-NIVEDI-Publication | |
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