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http://krishi.icar.gov.in/jspui/handle/123456789/71527| Title: | Synonymous codon usage pattern among the S, M, and L segments in crimean-congo hemorrhagic fever virus. |
| Other Titles: | Not Available |
| Authors: | Beelagi MS Kumar SS Indrabalan UB Patil SS Prasad A Suresh KP Kollur SP Jayappa VS Kakkalameli SB Srinivasa C Venkataravana PA |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::National Institute of Veterinary Epidemiology and Disease Informatics Department of Biotechnology and Bioinformatics, Faculty of Life Sciences, JSS Academy of Higher Education & Research, Mysuru-570015, India. Department of Studies in Food Technology, Shivagangotri, Davangere University, Davangere Karnataka-577 007, India. Department of Studies in Food Technology, Shivagangotri, Davangere University, Davangere Karnataka-577 007, India. Department of Studies in Food Technology, Shivagangotri, Davangere University, Davangere Karnataka-577 007, India. Department of Studies in Environmental Science, Shivagangotri, Davangere University, Davangere Karnataka-577 007, India. Department of Studies in Botany, Davangere University, Shivagangotri, Davangere Karnataka - 577 007, India. Department of Studies in Biotechnology, Davangere University, Shivagangotri, Davangere Karnataka-577 007, India |
| Published/ Complete Date: | 2021-04-30 |
| Project Code: | Not Available |
| Keywords: | CCHF virus S, M, L segments Homo sapiens Codon usage bias Mutational pressure Natural selection Host adaptation |
| Publisher: | Biomedical Informatics |
| Citation: | Beelagi MS, Kumar SS, Indrabalan UB, Patil SS, Prasad A, Suresh KP, Kollur SP, Jayappa VS, Kakkalameli SB, Srinivasa C, Venkataravana PA, Shivamallu C. Synonymous codon usage pattern among the S, M, and L segments in Crimean-congo hemorrhagic fever virus. Bioinformation. 2021 Apr 30;17(4):479-491. doi: 10.6026/97320630017479. PMID: 34602775; PMCID: PMC8450151 |
| Series/Report no.: | Not Available; |
| Abstract/Description: | Crimean-Congo hemorrhagic fever (CCHF) virus is one among the major zoonosis viral diseases that use the Hyalomma ticks as their transmission vector to cause viral infection to the human and mammalian community. The fatality of infectious is high across the world especially in Africa, Asia, Middle East, and Europe. This study regarding codon usage bias of S, M, and L segments of the CCHF virus pertaining to the host Homo sapiens, reveals in-depth information about the evolutionary characteristics of CCHFV. Relative Synonymous Codon Usage (RSCU), Effective number of codons (ENC) were calculated, to determine the codon usage pattern in each segment. Correlation analysis between Codon adaptation index (CAI), GRAVY (Hydrophobicity), AROMO (Aromaticity), and nucleotide composition revealed bias in the codon usage pattern. There was no strong codon bias found among any segments of the CCHF virus, indicating both the factors i.e., natural selection and mutational pressure shapes the codon usage bias |
| Description: | Not Available |
| ISSN: | 0973-2063 |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Bioinformation |
| Journal Type: | Peer reviewed journal |
| Volume No.: | 17 |
| Page Number: | 479-491 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | doi: 10.6026/97320630017479. |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/71527 |
| Appears in Collections: | AS-NIVEDI-Publication |
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