Efficient Block Designs for Mixed Level Factorial Microarray Experiments based on Baseline Parameterization

Abstract

A procedure of obtaining efficient block designs in block size 2 for n-factor mixed level factorial microarray experiments based on baseline parameterization has been given. A software module has been developed using C# programming language with ASP.NET platform for generation of efficient block designs in block size 2 for s1 × s2 ×× sn factorial experiments in v −1 arrays, where j s denotes the number of levels of jth factor and n denotes the number of factors and 1 n j j v s = = Π , the total number of treatment combinations. For n = 2, the software developed can also generate efficient block designs for 1 2 v −1≤ b ≤ ( v −1) + ( s −1)( s −1) , where b is the number of arrays.