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http://krishi.icar.gov.in/jspui/handle/123456789/8720| Title: | Pseudopeptides as novel antileptospiral agents: synthesis and spectral characterization |
| Other Titles: | Not Available |
| Authors: | Shivamallu C Sharanaiah U Kollur SP Mallesh NK Hosakere RD Balamurugan V |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::National Institute of Veterinary Epidemiology and Disease Informatics |
| Published/ Complete Date: | 2014-01-01 |
| Project Code: | Not Available |
| Keywords: | Anti-leptospiral activity Minimum inhibitory concentration Pseudo-peptide Spectroscopic technique |
| Publisher: | Pubmed |
| Citation: | Not Available |
| Series/Report no.: | Not Available; |
| Abstract/Description: | In this paper, we describe the synthesis of novel class of pseudo-peptides derived by coupling an amino acid with a heterocyclic moiety containing free amine group using suitable coupling agents. The synthesized compounds were characterized using spectral ((1)H NMR, (13)C NMR and MS) techniques. Preliminary pharmacological assays for Leptospirosis were studied by test tube dilution (TDT) and micro dilution technique (MDT). In particular, all the analyses led to the conclusion that the synthesized compound inhibiting the Leptospira a causal organism of Leptospirosis. |
| Description: | Not Available |
| ISSN: | 1386-1425 |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy |
| Volume No.: | 24 |
| Page Number: | 1152-1157 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | 10.1016/j.saa.2013.09.105. |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/8720 |
| Appears in Collections: | AS-NIVEDI-Publication |
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