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Please use this identifier to cite or link to this item:
http://krishi.icar.gov.in/jspui/handle/123456789/14232
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Vishnu, K.V. | en_US |
dc.contributor.author | Ajeeshkumar, K.K. | en_US |
dc.contributor.author | Remyakumari, K.R. | en_US |
dc.contributor.author | Ganesan, B. | en_US |
dc.contributor.author | Chatterjee, N.S | en_US |
dc.contributor.author | Lekshmi, R.G.K. | en_US |
dc.contributor.author | Shyni, K. | en_US |
dc.contributor.author | Suseela Mathew | en_US |
dc.date.accessioned | 2018-11-29T16:51:32Z | - |
dc.date.available | 2018-11-29T16:51:32Z | - |
dc.date.issued | 2017-02-20 | - |
dc.identifier.citation | Vishnu, K.V., Ajeeshkumar, K.K., Remyakumari, K.R., Ganesan, B, Chatterjee, N.S., Lekshmi, R.G.K., Shyni, K. and Suseela Mathew (2017) - Gastroprotective effect of sardine oil (Sardinella longiceps) against HCl/ethanol induced ulceration in Wistar rats, Intl J. Fish. Aquatic Stud. 5(2):118-124. | en_US |
dc.identifier.issn | 2347-5129(Online) 2394-0506 (Print) | - |
dc.identifier.uri | http://krishi.icar.gov.in/jspui/handle/123456789/14232 | - |
dc.description | Not Available | en_US |
dc.description.abstract | Sardine oil is rich in n-3 polyunsaturated fatty acids (PUFAs) like EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). The oil showed a significant proportion of n-3 polyunsaturated fatty acids (PUFAs), the percentages of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) being 16 and 14% respectively. Gastroprotective activities of sardine oil (Sardinella longiceps) were examined in ulcer induced rats. Sardine oil has significant anti-secretory activity as evidenced by decreased gastric fluid volume, total acidity, and increase in the pH of the gastric fluid in ethanol/HCl induced rats. Our studies also revealed that pretreatment with sardine oil significantly reduced the number of ulcer, ulcer score and ulcer index in ethanol/HCl treated rats. The anti-ulcer activity of sardine oil is further supported by histopathological study, which showed protection of the mucosal layer from ulceration. Furthermore, this oil showed significant reversal of ethanol-diminished activity in antioxidant enzymes, such as SOD, CAT, and GSH. The overall findings conclude that oil of Sardinella longiceps has a significant proportion of n-3 polyunsaturated fatty acids and potent anti-ulcer effects. Hence, sardine oil may be a suitable natural source for the prevention and treatment of gastric lesions. | en_US |
dc.description.sponsorship | Not Available | en_US |
dc.language.iso | English | en_US |
dc.publisher | IIJFAS | en_US |
dc.relation.ispartofseries | Not Available; | - |
dc.subject | Sardine oil | en_US |
dc.subject | anti-ulcer | en_US |
dc.subject | n-3 PUFA | en_US |
dc.subject | gastic mucosa | en_US |
dc.title | Gastroprotective effect of Sardine oil(Sardinella longiceps) against HCL/ethanol induced ulceration in Wistar rats | en_US |
dc.title.alternative | Not Available | en_US |
dc.type | Research Paper | en_US |
dc.publication.projectcode | Not Available | en_US |
dc.publication.journalname | International Journal of Fisheries and Aquatic Studies | en_US |
dc.publication.volumeno | 5(2) | en_US |
dc.publication.pagenumber | 118-124 | en_US |
dc.publication.divisionUnit | Not Available | en_US |
dc.publication.sourceUrl | http://dx.doi.org/10.22271/fish | en_US |
dc.publication.authorAffiliation | ICAR::Central Institute of Fisheries Technology | en_US |
dc.ICARdataUseLicence | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf | en_US |
Appears in Collections: | FS-CIFT-Publication |
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