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http://krishi.icar.gov.in/jspui/handle/123456789/19851| Title: | Molecular epidemiological analysis of wild animal rabies isolates from India |
| Other Titles: | Not Available |
| Authors: | Manjunatha Reddy GB Singh R Singh KP Sharma AK Vineetha S Saminathan M Sajjanar B |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::National Institute of Veterinary Epidemiology and Disease Informatics ICAR::Indian Veterinary Research Institute |
| Published/ Complete Date: | 2019-03-04 |
| Project Code: | Not Available |
| Keywords: | India nucleoprotein gene phylogenetic analysis rabies virus wild animals |
| Publisher: | Veterinary World |
| Citation: | Not Available |
| Series/Report no.: | Not Available; |
| Abstract/Description: | Aim: This study was conducted to know the genetic variability of rabies viruses (RVs) from wild animals in India. Materials and Methods: A total of 20 rabies suspected brain samples of wild animals from different states of India were included in the study. The samples were subjected for direct fluorescent antibody test (dFAT), reverse transcription polymerase chain reaction (RT-PCR), and quantitative reverse transcriptase real-time PCR (RT-qPCR). The phylogenetic analysis of partial nucleoprotein gene sequences was performed. Results: Of 20 samples, 11, 10, and 12 cases were found positive by dFAT, RT-PCR, and RT-qPCR, respectively. Phylogenetic analysis showed that all Indian wild RVs isolates belonged to classical genotype 1 of Lyssavirus and were closely related to Arctic/Arctic-like single cluster indicating the possibility of a spillover of rabies among different species. Conclusion: The results indicated the circulation of similar RVs in sylvatic and urban cycles in India. However, understanding the role of wild animals as reservoir host needs to be studied in India. |
| Description: | Not Available |
| ISSN: | 2231-0916 |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Veterinary World |
| NAAS Rating: | Not Available |
| Volume No.: | 12(3) |
| Page Number: | 352-357 |
| Name of the Division/Regional Station: | Animal science |
| Source, DOI or any other URL: | https://dx.doi.org/10.14202%2Fvetworld.2019.352-357 |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/19851 |
| Appears in Collections: | AS-NIVEDI-Publication |
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