KRISHI
ICAR RESEARCH DATA REPOSITORY FOR KNOWLEDGE MANAGEMENT
(An Institutional Publication and Data Inventory Repository)
"Not Available": Please do not remove the default option "Not Available" for the fields where metadata information is not available
"1001-01-01": Date not available or not applicable for filling metadata infromation
"1001-01-01": Date not available or not applicable for filling metadata infromation
Please use this identifier to cite or link to this item:
http://krishi.icar.gov.in/jspui/handle/123456789/21437
Title: | Effect of dietary organic selenium (Se) on immune response, hepatic antioxidant status, selenoprotein gene expression and meat oxidative stability in lambs |
Other Titles: | Not Available |
Authors: | Suganthi RU Ghosh J Malik PK Awachat VB Krishnamoorthy P Pal DT Nongkhlaw SS |
ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
Author's Affiliated institute: | ICAR::National Institute of Animal Nutrition and Physiology ICAR::National Institute of Veterinary Epidemiology and Disease Informatics |
Published/ Complete Date: | 2019-06-25 |
Project Code: | Not Available |
Keywords: | antioxidant status gene expression immune response lambs meat quality selenium yeasts |
Publisher: | Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences |
Citation: | Not Available |
Series/Report no.: | Not Available; |
Abstract/Description: | The objective of the study was to examine the effects of different doses of dietary organic selenium (Se) on humoral immune response, hepatic antioxidant status, mRNA expression of key selenoproteins and oxidative stability of lamb meat. Twenty lambs aging 5–6 months received during a 90-day period a basal diet unsupplemented or supplemented with 0.5, 1.5 or 4.5 ppm Se (selenized yeasts). After experimental period, immune response against Peste des petits ruminants (PPR) virus vaccine, hepatic antioxidant status, selenoproteins gene expression, histology of liver, kidney, spleen and thymus, and meat oxidative stability after 0, 3, 7 and 10 days of storage were studied. Significantly higher serum PPR antibody titre and hepatic total antioxidant capacity in lambs fed diet supplemented with 1.5 and 4.5 ppm Se were shown. Gene expression of glutathione peroxidase 1 (GPX1) and GPX3 was increased in group with 0.5 ppm Se supplementation. While selenoprotein 15 and iodothyronine deiodinase 1 (DIO1) mRNA levels were not influenced by supranutritional Se supplementation, DIO3 mRNA level was upregulated at 4.5 ppm Se addition. Selenoprotein P and W1 gene expression were significantly upregulated by 1.5 and 4.5 ppm Se supplementation, respectively. Thioredoxin reductase 1 gene expression was decreased by 4.5 ppm Se. No appreciable differences in meat lipid oxidation were observed amongst treatments. So, feeding 1.5 ppm organic Se could be beneficial in improving humoral immune response to PPR vaccine and hepatic antioxidant status in lambs. Further, the expression of genes encoding selenoproteinases depends on their type and dose of Se in the diet. The studied Se doses did not induce toxicity in organs but exhibited limited potential to enhance meat oxidative stability. |
Description: | Not Available |
ISSN: | 1230-1388 |
Type(s) of content: | Research Paper |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Journal of Animal and Feed Sciences |
NAAS Rating: | 7.15 |
Volume No.: | 28 |
Page Number: | 138-148 |
Name of the Division/Regional Station: | Not Available |
Source, DOI or any other URL: | http://www.jafs.com.pl/Effect-of-dietary-organic-selenium-Se-on-immune-response-hepatic-antioxidant-status,109283,0,2.html |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/21437 |
Appears in Collections: | AS-NIVEDI-Publication |
Files in This Item:
There are no files associated with this item.
Items in KRISHI are protected by copyright, with all rights reserved, unless otherwise indicated.