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http://krishi.icar.gov.in/jspui/handle/123456789/28688| Title: | Genetic analysis of the matrix and non-structural genes of equine influenza virus (H3N8) from epizootic of 2008–2009 in India |
| Other Titles: | Not Available |
| Authors: | Nitin Virmani |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::National Research Centre on Equines |
| Published/ Complete Date: | 2011-04-14 |
| Project Code: | Not Available |
| Keywords: | equine influenza |
| Publisher: | Not Available |
| Citation: | Not Available |
| Series/Report no.: | Not Available; |
| Abstract/Description: | India faced an epizootic of equine influenza in 2008–2009. The isolated viruses were typed as H3N8 and grouped with the clade 2 viruses of Florida sublineage on the basis of haemagglutinin (HA) gene sequence analysis. This report describes the genetic analysis and selection pressure of matrix (M) and non-structural 1 (NS1) genes of the Indian isolates. All isolates shared 98.41% and 99.54% homology with other clade 2 viruses of Asian origin for M1 and M2 amino acid (aa) sequences, respectively. There were 3 and 4 unique aa residue changes respectively in M1 and M2 proteins in all Asian isolates. Phylogenetic analysis revealed clustering of Indian and Chinese isolates in a separate group designated here as Asian clade for M gene. Indian and Chinese isolates shared homology ranging from 98.17% to 99.08% at aa level. The M and NS1 genes were under negative selection pressure with estimated magnitude of pressure (v) 0.054, 0.581 and 0.30 for M1, M2 and NS1, respectively. |
| Description: | Not Available |
| ISSN: | Not Available |
| Type(s) of content: | Article |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Veterinary Microbiology |
| NAAS Rating: | 9.03 |
| Volume No.: | Not Available |
| Page Number: | Not Available |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | doi:10.1016/j.vetmic.2011.04.011 |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/28688 |
| Appears in Collections: | AS-NRCE-Publication |
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