KRISHI
ICAR RESEARCH DATA REPOSITORY FOR KNOWLEDGE MANAGEMENT
(An Institutional Publication and Data Inventory Repository)
"Not Available": Please do not remove the default option "Not Available" for the fields where metadata information is not available
"1001-01-01": Date not available or not applicable for filling metadata infromation
"1001-01-01": Date not available or not applicable for filling metadata infromation
Please use this identifier to cite or link to this item:
http://krishi.icar.gov.in/jspui/handle/123456789/31651
Title: | Key enzymes and proteins of crop insects as candidate for RNAi based gene silencing |
Other Titles: | Not Available |
Authors: | Kola VSR, Renuka P, Madhav MS, and Mangrauthia SK |
ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
Author's Affiliated institute: | ICAR-Indian Institute of Rice Research Hyderabad |
Published/ Complete Date: | 2013-06-01 |
Project Code: | Not Available |
Keywords: | dicer; insecticide; off target; resistance; siRNA |
Publisher: | Open Access Frontiers |
Citation: | Kola VSR, Renuka P, Madhav MS, and Mangrauthia SK* (2015). Key enzymes and proteins of crop insects as candidate for RNAi based gene silencing. Frontiers in Physiology, 6:119. |
Series/Report no.: | Not Available; |
Abstract/Description: | RNA interference (RNAi) is a mechanism of homology dependent gene silencing present in plants and animals. It operates through 21-24 nucleotides small RNAs which are processed through a set of core enzymatic machinery that involves Dicer and Argonaute proteins. In recent past, the technology has been well appreciated toward the control of plant pathogens and insects through suppression of key genes/proteins of infecting organisms. The genes encoding key enzymes/proteins with the great potential for developing an effective insect control by RNAi approach are actylcholinesterase, cytochrome P450 enzymes, amino peptidase N, allatostatin, allatotropin, tryptophan oxygenase, arginine kinase, vacuolar ATPase, chitin synthase, glutathione-S-transferase, catalase, trehalose phosphate synthase, vitellogenin, hydroxy-3-methylglutaryl coenzyme A reductase, and hormone receptor genes. Through various studies, it is demonstrated that RNAi is a reliable molecular tool which offers great promises in meeting the challenges imposed by crop insects with careful selection of key enzymes/proteins. Utilization of RNAi tool to target some of these key proteins of crop insects through various approaches is described here. The major challenges of RNAi based insect control such as identifying potential targets, delivery methods of silencing trigger, off target effects, and complexity of insect biology are very well illustrated. Further, required efforts to address these challenges are also discussed. |
Description: | Not Available |
ISSN: | Not Available |
Type(s) of content: | Article |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Frontiers in Physiology |
NAAS Rating: | 9.37 |
Volume No.: | 6 |
Page Number: | 119 |
Name of the Division/Regional Station: | Biotechnology |
Source, DOI or any other URL: | doi: 10.3389/fphys.2015.00119 |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/31651 |
Appears in Collections: | CS-IIRR-Publication |
Files in This Item:
There are no files associated with this item.
Items in KRISHI are protected by copyright, with all rights reserved, unless otherwise indicated.