Skip navigation
DSpace logo
  • Home
  • Browse
    • SMD
      & Institutes
    • Browse Items by:
    • Published/ Complete Date
    • Author/ PI/CoPI
    • Title
    • Keyword (Publication)
  • Sign on to:
    • My KRISHI
    • Receive email
      updates
    • Edit Profile
ICAR logo

KRISHI

ICAR RESEARCH DATA REPOSITORY FOR KNOWLEDGE MANAGEMENT
(An Institutional Publication and Data Inventory Repository)


  1. KRISHI Publication and Data Inventory Repository
  2. Fisheries A6
  3. ICAR-Central Institute of Fisheries Technology I5
  4. FS-CIFT-Publication
"Not Available": Please do not remove the default option "Not Available" for the fields where metadata information is not available
"1001-01-01": Date not available or not applicable for filling metadata infromation
Please use this identifier to cite or link to this item: http://krishi.icar.gov.in/jspui/handle/123456789/47491
Title: Determination of biosafety of the antibiotic oxytetracycline hydrochloride in Pangasianodonhypophthalmus
Other Titles: Not Available
Authors: Manna, S. K.
Bera, A. K.
Das, N.
Bandopadhyay, C.
Baitha, R.
Ghadei, S. S.
Das, B. K.,
Ashok Kumar, K.
Rajisha, R.
Nanitha Krishna
Patil, P. K.
ICAR Data Use Licennce: http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf
Author's Affiliated institute: ICAR::Central Inland Fisheries Research Institute
ICAR::Central Institute of Fisheries Technology
ICAR::Central Institute of Brackishwater Aquaculture
Published/ Complete Date: 2021-06
Project Code: Not Available
Keywords: biochemistry
haematology
oxytetracycline
Pangasianodon hypophthalmus
safety
Publisher: Wiley
Citation: Manna, S. K., Bera, A. K., Das, N., Bandopadhyay, C., Baitha, R., Ghadei, S. S., Das, B. K., Ashok Kumar, K., Rajisha, R., Nanitha Krishna and Patil, P. K. (2021) Determination of biosafety of the antibiotic Oxytetracycline hydrochloride in Pangasianodon hypophthalmus. Aquac. Res. 52(6): 2470-2480.
Series/Report no.: Not Available;
Abstract/Description: Pangasianodon hypophthalmus is one of the most important aquaculture species in Southeast Asia, with a significant contribution to the world fish basket. Like other crops, the striped catfish suffers from bacterial diseases that demand the use of antibiotics. The present study has evaluated the safety of oxytetracycline, one of the approved and commonly used antibiotics, in this species. Juvenile stages of the fish (31.16 ± 1.03 g) were administered with the antibiotic in feed at the dose rate of 80–800 mg kg−1 body weight daily for 30 days, followed by 10 days of withdrawal observation. Fish health was assessed by the study of behaviour and feed intake, haematology, blood biochemistry, and histopathology. Results showed that up to 30 days of antibiotic treatment resulted in no significant toxic effects in terms of behaviour and fish mortality. However, fish suffered from reduced feed intake and hepatotoxicity evidenced by proliferative and degenerative changes of hepatocytes, and increase in AST and ALT enzyme activities, especially in 400–800 mg kg−1 doses which, however, recovered after withdrawal of the drug. Although few fish died from a bacterial infection at the lowest concentration of the drug used, fish were able to mount adaptive physiological responses best at 80 mg kg−1 fish dosage. The study establishes that in-feed administration of the antibiotic oxytetracycline @ 80 mg kg−1 fish biomass is safe for therapeutic use in P. hypophthalmus.
Description: Not Available
ISSN: 1355-557X
Type(s) of content: Research Paper
Sponsors: Not Available
Language: English
Name of Journal: Aquaculture Research
Journal Type: International
NAAS Rating: 7.75
Impact Factor: 1.75
Volume No.: 52(6)
Page Number: 2470-2480
Name of the Division/Regional Station: Not Available
Source, DOI or any other URL: https://doi.org/10.1111/are.15096
URI: http://krishi.icar.gov.in/jspui/handle/123456789/47491
Appears in Collections:FS-CIFT-Publication

Files in This Item:
There are no files associated with this item.
Show full item record


Items in KRISHI are protected by copyright, with all rights reserved, unless otherwise indicated.

  File Downloads  

May 2022: 67321 Apr 2022: 94186 Mar 2022: 96096 Feb 2022: 93736 Jan 2022: 86503 Dec 2021: 98347

Total Download
2679302

(Also includes document to fetched through computer programme by other sites)
( From May 2017 )

ICAR Data Use Licence
Disclaimer
©  2016 All Rights Reserved  • 
Indian Council of Agricultural Research
Krishi Bhavan, Dr. Rajendra Prasad Road, New Delhi-110 001. INDIA

INDEXED BY

KRISHI: Inter Portal Harvester

DOAR
Theme by Logo CINECA Reports

DSpace Software Copyright © 2002-2013  Duraspace - Feedback