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http://krishi.icar.gov.in/jspui/handle/123456789/51107
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Smrutirekha Mallick | - |
dc.contributor.author | Saravanan S | - |
dc.contributor.author | J.K. Biswal | - |
dc.contributor.author | Rajeev Ranjan | - |
dc.contributor.author | J.K. Mohapatra | - |
dc.contributor.author | Aditya Prasad Sahoo | - |
dc.date.accessioned | 2021-07-29T09:34:40Z | - |
dc.date.available | 2021-07-29T09:34:40Z | - |
dc.date.issued | 2021-7-1 | - |
dc.identifier.citation | Mallick, S., Subramaniam, S., Biswal, J.K. et al. Short communication: preliminary observations on the serum levels of HSP70 and its correlation with serum cortisol, thyroid hormones, and acute-phase protein concentration in cattle naturally infected with foot-and-mouth disease virus. Trop Anim Heal | en_US |
dc.identifier.isbn | Not Available | en_US |
dc.identifier.issn | 0049-4747 | en_US |
dc.identifier.uri | http://krishi.icar.gov.in/jspui/handle/123456789/51107 | - |
dc.description | Not Available | en_US |
dc.description.abstract | The study aimed to explore the serum levels of HSP70 and identify its possible association with serum cortisol, thyroid hormones, and acute-phase protein concentrations in cattle naturally infected with foot-and-mouth disease (FMD) virus. After the FMD outbreak in an organized dairy cattle farm in India, blood samples were obtained from clinically infected (n?=?40) and apparently healthy (n?=?30) animals. Samples were processed and tested by an in-house DIVA assay for confirmation of FMD infection. Serum was analyzed for HSP70, cortisol, T4, T3, haptoglobin, and serum amyloid A by enzyme-linked immunosorbent assay (ELISA). HSP70 concentrations were significantly higher in the serum of clinically infected cattle (p?<?0.01) than the healthy group. To the best of our knowledge, this is the first report describing the elevated serum levels of HSP70 under infectious diseases of bovines. Cortisol (p?<?0.05), haptoglobin (p?<?0.001), and serum amyloid A (p?<?0.05) concentrations also markedly increased in the diseased animals; however, no differences (p?>?0.05) were found in T4 and T3 levels between healthy and infected cattle. Elevated HSP70 concentration correlated positively with high cortisol (p?<?0.05) and haptoglobin (p?<?0.001) levels suggesting an essential link between these acute events during clinical infectious phase of FMD. | en_US |
dc.language.iso | English | en_US |
dc.publisher | Not Available | en_US |
dc.subject | Serum HSP70,Cortisol,Thyroid hormone,Acute Phase Proteins,Foot and Mouth Disease | en_US |
dc.title | Short communication: preliminary observations on the serum levels of HSP70 and its correlation with serum cortisol, thyroid hormones, and acute-phase protein concentration in cattle naturally infected with foot-and-mouth disease virus. | en_US |
dc.type | Research Paper | en_US |
dc.publication.journalname | Tropical Animal Health and Production | en_US |
dc.publication.submitter | From ARMS | - |
Appears in Collections: | AS-PDFMD-Publication |
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