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http://krishi.icar.gov.in/jspui/handle/123456789/51395
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Smrutirekha Mallick, Saravanan Subramaniam, Jitendra Kumar Biswal, Rajeev Ranjan, Jajati Keshari Mohapatra, Aditya Prasad Sahooot Available | en_US |
dc.date.accessioned | 2021-07-30T05:39:51Z | - |
dc.date.available | 2021-07-30T05:39:51Z | - |
dc.date.issued | 2021-07-25 | - |
dc.identifier.citation | Mallick S., Subramaniam S., Biswal J K., Ranjan R., Mohapatra J K. and Sahoo A P. Trop Anim Health Prod . 2021 Jul 22;53(4):408. | en_US |
dc.identifier.issn | Not Available | - |
dc.identifier.uri | http://krishi.icar.gov.in/jspui/handle/123456789/51395 | - |
dc.description | Not Available | en_US |
dc.description.abstract | The study aimed to explore the serum levels of HSP70 and identify its possible association with serum cortisol, thyroid hormones, and acute-phase protein concentrations in cattle naturally infected with foot-and-mouth disease (FMD) virus. After the FMD outbreak in an organized dairy cattle farm in India, blood samples were obtained from clinically infected (n = 40) and apparently healthy (n = 30) animals. Samples were processed and tested by an in-house DIVA assay for confirmation of FMD infection. Serum was analyzed for HSP70, cortisol, T4, T3, haptoglobin, and serum amyloid A by enzyme-linked immunosorbent assay (ELISA). HSP70 concentrations were significantly higher in the serum of clinically infected cattle (p < 0.01) than the healthy group. To the best of our knowledge, this is the first report describing the elevated serum levels of HSP70 under infectious diseases of bovines. Cortisol (p < 0.05), haptoglobin (p < 0.001), and serum amyloid A (p < 0.05) concentrations also markedly increased in the diseased animals; however, no differences (p > 0.05) were found in T4 and T3 levels between healthy and infected cattle. Elevated HSP70 concentration correlated positively with high cortisol (p < 0.05) and haptoglobin (p < 0.001) levels suggesting an essential link between these acute events during clinical infectious phase of FMD. | en_US |
dc.description.sponsorship | ICAR-Directorate of Foot and Mouth Disease | en_US |
dc.language.iso | English | en_US |
dc.publisher | SPRINGER | en_US |
dc.relation.ispartofseries | Not Available; | - |
dc.subject | Acute-phase proteins; Cortisol; Foot-and-mouth disease; Serum HSP70; Thyroid hormone. | en_US |
dc.title | Short communication: preliminary observations on the serum levels of HSP70 and its correlation with serum cortisol, thyroid hormones, and acute-phase protein concentration in cattle naturally infected with foot-and-mouth disease virus | en_US |
dc.title.alternative | Not Available | en_US |
dc.type | Research Paper | en_US |
dc.publication.projectcode | Not Available | en_US |
dc.publication.journalname | Tropical Animal Health and Production | en_US |
dc.publication.volumeno | 53 (4) | en_US |
dc.publication.pagenumber | 408 | en_US |
dc.publication.divisionUnit | Not Available | en_US |
dc.publication.sourceUrl | doi: 10.1007/s11250-021-02814-z. | en_US |
dc.publication.authorAffiliation | ICAR-DIRECTORATE OF FOOT AND MOUTH DISEASE | en_US |
dc.ICARdataUseLicence | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf | en_US |
dc.publication.journaltype | Research | en_US |
dc.publication.naasrating | 7.33 | en_US |
dc.publication.impactfactor | 1.559 | en_US |
Appears in Collections: | AS-PDFMD-Publication |
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