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http://krishi.icar.gov.in/jspui/handle/123456789/5952| Title: | Antiviral activity of crude extracts of Eugenia jambolana Lam. against Highly pathogenic avian influenza (H5N1) virus |
| Other Titles: | Not Available |
| Authors: | Sood, R. Swarup, D. Bhatia, S. Kulkarni, D.D. Dey, S. Saini, M. Dubey, S. C. |
| Published/ Complete Date: | 2012-03-01 |
| Project Code: | Not Available |
| Keywords: | Antiviral activity of crude extracts of Eugenia jambolana Lam Avian influenza (H5N1) virus India |
| Publisher: | NISCAIR-CSIR, India |
| Citation: | Sood, R., Swarup, D., Bhatia, S., Kulkarni, D.D., Dey, S., Saini, M., and Dubey, S. C. (2012). Antiviral activity of crude extracts of Eugenia jambolana Lam. against Highly pathogenic avian influenza (H5N1) virus. Indian J Exp Biol. 2012 Mar;50(3):179-86 |
| Series/Report no.: | Not Available; |
| Abstract/Description: | Crude extracts of leaves and bark of E. jambolana were tested for antiviral activity against highly pathogenic avian influenza virus (H5N1) by CPE reduction assay in three different layouts to elucidate virucidal, post-exposure and preexposure antiviral activity of the extracts. The cold and hot aqueous extracts of bark and hot aqueous extract of leaves of E. jambolana showed significant virucidal activity (100% inhibition) which was further confirmed in virus yield reduction assay (-98 to 99% reduction) and by egg based in ovo assay. The selective index (CC50/EC50) of hot aqueous extract (248) and cold aqueous extract (43.5) of bark of E. jambolana showed their antiviral potential against H5N1 virus. The significant virucidal activity of leaves and bark of E. jambolana merits further investigation as it may provide alternative antiviral agent for managing avian influenza infections in poultry farms and potential avian-human transmission. |
| Description: | Not Available |
| ISSN: | 0975-1009 |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Indian Journal of Experimental Biology |
| NAAS Rating: | 6.78 |
| Volume No.: | 50(3) |
| Page Number: | 179-86 |
| Name of the Division/Regional Station: | Diagnostic II Lab |
| Source, DOI or any other URL: | https://www.ncbi.nlm.nih.gov/pubmed/22439432 |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/5952 |
| Appears in Collections: | AS-NIHSAD-Publication |
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