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http://krishi.icar.gov.in/jspui/handle/123456789/70619
Title: | Virus secret revealed: ribosome profiling uncovers unannotated translation initiation sites and hidden open-reading frame in the TYLCTHV genome |
Other Titles: | Not Available |
Authors: | Kutubuddin A Molla |
ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
Author's Affiliated institute: | ICAR::National Rice Research Institute |
Published/ Complete Date: | 2022-02-03 |
Project Code: | Not Available |
Keywords: | Virus, Ribosome profiling, Translation, open-reading frame, Viral gene |
Publisher: | Oxford University Press |
Citation: | Kutubuddin A Molla, Virus secret revealed: ribosome profiling uncovers unannotated translation initiation sites and hidden open-reading frame in the TYLCTHV genome, The Plant Cell, 2022;, koac034, https://doi.org/10.1093/plcell/koac034 |
Series/Report no.: | Not Available; |
Abstract/Description: | Viruses are too small to be seen in a light microscope, yet they cause havoc in plants as well as animal communities. In the midst of a viral pandemic, who would know better than us how much damage this tiny invisible foe can cause. Viruses need to produce numerous proteins for replication, movement, and pathogenesis. Having a tiny genome, viruses use non-conventional strategies like initiating protein synthesis from un-annotated sites to increase their coding capacity (Ho et al., 2021). Accurate annotation of viral genes is crucial to developing antiviral strategies. However, deciphering a full set of viral genes is a great challenge as viruses use hidden open-reading frames (ORFs) with unanticipated translation initiation sites (TISs). |
Description: | Not Available |
Type(s) of content: | Review Paper |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Plant Cell |
Volume No.: | Not Available |
Page Number: | Not Available |
Name of the Division/Regional Station: | Crop improvement division |
Source, DOI or any other URL: | https://doi.org/10.1093/plcell/koac034 |
URI: | https://doi.org/10.1093/plcell/koac034 http://krishi.icar.gov.in/jspui/handle/123456789/70619 |
Appears in Collections: | CS-NRRI-Publication |
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