Record Details

Association-Dissociation Behavior of Sesame alpha-Globulin in Electrolyte Solutions

IR@CSIR-CFTRI

View Archive Info
 
 
Field Value
 
Relation http://ir.cftri.com/1612/
JBC-01-77
 
Title Association-Dissociation Behavior of Sesame alpha-Globulin in Electrolyte Solutions
 
Creator Prakash, V.
Nandi, P. K.
 
Subject 29 Protein Chemistry
22 Legumes-Pulses
 
Description The major protein fraction, alpha-globulin, of sesame seed CS’esamum indicum L.) contains subunits
which are associated predominantly by hydrophobic interactions. Effects of various salts show the
following effectiveness of anions in dissociating the proteins, SO,*- < Cl- < Br- < C104- < SCN- 4
I- < CCl,COO-, the first two members being association-inducing ions. CC1,COONa is found to be
the most effective among the series in causing dissociation. The cations Lit, Na+, K+, and Cs+ induce
association, the order of effectiveness being Cs+ - K+ > Na+ > IA+. The low concentration of salts
(anions) necessary to induce dissociation does not involve a detectable change in protein conforma-
tion. The discrepancy between the effectiveness of the anions in dissociating the protein and the
Hofmeister pattern of these ions has been discussed.
 
Date 1977
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Rights —
 
Identifier http://ir.cftri.com/1612/1/JBC_252_240_-_243_1977.pdf
Prakash, V. and Nandi, P. K. (1977) Association-Dissociation Behavior of Sesame alpha-Globulin in Electrolyte Solutions. Journal of Biological Chemistry, 252 (1). pp. 240-243.