ICAR Research Data Repository for Knowledge Management
The Interaction of Vincristine with Calf Brain Tubulin
IR@CSIR-CFTRI
View Archive Info| Field | Value | |
| Relation |
http://ir.cftri.com/1613/
JBC-02-83 |
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| Title |
The Interaction of Vincristine with Calf Brain Tubulin
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| Creator |
Prakash, V.
Timasheff, S. N. |
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| Subject |
29 Protein Chemistry
02 Alkaloids Chemistry |
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| Description |
The interaction of the antimitotic drug vincristine with tubulin has been investigated by the techniques of self-assembly, velocity sedimentation, fluorescence, circular dichroism, and differential spectroscopy. Vin- cristine has been shown to inhibit the self-assembly of tubulin into microtubules at substoichiometric concen- trations. The sedimentation velocity patterns at low vincristine concentration ( |
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| Date |
1983
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Language |
en
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| Identifier |
http://ir.cftri.com/1613/1/JBC_258_1689_-_1697_1983.pdf
Prakash, V. and Timasheff, S. N. (1983) The Interaction of Vincristine with Calf Brain Tubulin. Journal of Biological Chemistry, 258 (3). pp. 1689-1697. |
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