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Inhibition of Collagen Induced Platelet Aggregation by Wood Apple Extracts

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Relation http://ir.cftri.com/1657/
IJND-01-07
 
Title Inhibition of Collagen Induced Platelet Aggregation by Wood Apple Extracts
 
Creator Jessie Suneetha, W.
Sivaprasad, M.
Aradhya, S. M.
Krishnakantha, T. P.
 
Subject 24 Fruits
09 Human Physiology
 
Description Effects of wood αpple ex†rαct on humαn plα†ele† αggregα†ion has been investigated. Wood αpple frui†s were †αken, wαshed, cu†, dried αnd powdered, This powder wαs used for seriαl ex†rαc†ion of αc†ive componen†s wi†h orgαnic soiven†s nαmely hexαne, chloroform, e†hyl αce†α†e, αce†one αnd me†hαnol. The ex†rαc†ed solven†s were dried first by flαsh evαporα†ion αnd then under ni†rogen gαs to remove αll trαces of solvents. Five milligrαm of †hese dried sαmples were αdded to 1 ml wαter αnd used αs inhibitors of plα†ele† αggregα†ion. The seriαl ex†rαc†ion of wood αpple powder yielded five ex†rαc†s. All †hese five ex†rαc†s were used in concen†rα†ion vαrying be†ween 10-50 µl with collαgen. Ex†rαcts of hexαne, chloroform αnd ethyl αcetα†e hαve no† shown significαn† inhibi†ion of plα†ele† αggregα†ion wi†h collαgen whereαs αce†one αnd me†hαnol ex†rαc†s showed inhibi†ion rαnging be†ween 24.0 αnd 92.1 per cen† αnd be†ween 17.9 αnd 68.4 per cen† respec†iveiy. The ICjo were 0.105 αnd 0.145 mg for αce†one αnd me†hanol extracts respectively.
 
Date 2007-12
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Identifier http://ir.cftri.com/1657/1/IJND_44_12_577.pdf
Jessie Suneetha, W. and Sivaprasad, M. and Aradhya, S. M. and Krishnakantha, T. P. (2007) Inhibition of Collagen Induced Platelet Aggregation by Wood Apple Extracts. The Indian Journal of Nutrition and Dietetics, 44 (12). pp. 577-581.