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Assessment of serum macro and trace element homeostasis and the complexity of inter-element relations in bipolar mood disorders.

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Title Assessment of serum macro and trace element homeostasis and the complexity of inter-element relations in bipolar mood disorders.
 
Creator Mustak, Mohammed S
Sathyanarayana Rao, T. S.
Shanmugavelu, P.
Sundar, N. M. Shama
Rani, B. Menon
Rao, R. V.
Rao, K. S. J.
 
Subject 09 Human Physiology
 
Description BACKGROUND: Bipolar disorders are complex neuropsychiatric in nature and are clinically classified as Type I, Type II, and Type V. The etiological factors include environmental-genetic inter-relations. Trace metals play a significant role in neurological disorders. There is very limited information on the role of macro and trace elements in bipolar disorders. METHODS: Trace elements namely Na, K, S, Ca, Mg, P, Cu, Fe, Zn, Mn and Al were analyzed in serum samples of 3 bipolar types: bipolar I, bipolar II and bipolar V with a control group using inductively coupled plasma-atomic emission spectrometry (ICP-AES). The patients were assessed as per the standard diagnostic criteria and classified into the bipolar type I, II hypomanic, II depressives and V. RESULTS: In bipolar I (mania), Na, K, P, Cu, Al and Mn were increased significantly (p
 
Date 2008
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
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Identifier http://ir.cftri.com/1790/1/Clinica%20Chimica%20Acta%2C%20Volume%20394%2C%20Issues%201%E2%80%932%2C%20August%202008%2C%20Pages%2047-53.pdf
Mustak, Mohammed S and Sathyanarayana Rao, T. S. and Shanmugavelu, P. and Sundar, N. M. Shama and Rani, B. Menon and Rao, R. V. and Rao, K. S. J. (2008) Assessment of serum macro and trace element homeostasis and the complexity of inter-element relations in bipolar mood disorders. Clinica Chimica Acta; International Journal of Clinical Chemistry, 394 (1-2). pp. 47-53. ISSN 0009-8981