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Isolation and characterization of antioxidant and antibacterial compound from mango ginger (Curcuma amada Roxb.) rhizome.

IR@CSIR-CFTRI

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Relation http://ir.cftri.com/1896/
JCHR-01-07
 
Title Isolation and characterization of antioxidant and antibacterial compound from mango ginger (Curcuma amada Roxb.) rhizome.
 
Creator Policegoudra, R. S.
Abiraj, K.
Channe Gowda, D.
Aradhya, S. M.
 
Subject 30 Spices/Condiments
32 Antioxidants
 
Description The chloroform extract of mango ginger (Curcuma amada Roxb.) rhizome was subjected to antioxidant activity-guided purification by repeated silica gel column chromatography to obtain a pure antioxidant compound. The structure was deduced by analyzing UV, IR, liquid chromatography-mass spectrometry (LC-MS) and two-dimensional heteronuclear multiple quantum coherence transfer spectroscopy (2D-HMQCT) NMR spectral data, and named it as "Amadannulen", a novel compound. It exhibited DPPH radical scavenging activity, super oxide radical scavenging activity, lipid peroxidation inhibitory activity and metal chelating activity. Amadannulen also showed antibacterial activity against both Gram-positive and Gram-negative bacteria tested. It also exhibited bactericidal activity against M. luteus, B. cereus and B. subtilis.
 
Date 2007
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Rights —
 
Identifier http://ir.cftri.com/1896/1/Journal_of_Chromatography_B_852%281-2%29__2007_40-48.pdf
Policegoudra, R. S. and Abiraj, K. and Channe Gowda, D. and Aradhya, S. M. (2007) Isolation and characterization of antioxidant and antibacterial compound from mango ginger (Curcuma amada Roxb.) rhizome. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 852 (1-2). pp. 40-8. ISSN 1570-0232