ICAR Research Data Repository for Knowledge Management
Sclerotiorin from Penicillium frequentans, a potent inhibitor of aldose reductase.
IR@CSIR-CFTRI
View Archive Info| Field | Value | |
| Relation |
http://ir.cftri.com/1921/
BL-01-06 |
|
| Title |
Sclerotiorin from Penicillium frequentans, a potent inhibitor of aldose reductase.
|
|
| Creator |
Chidananda, C.
Jaganmohan Rao, L. Sattur, A. P. |
|
| Subject |
05 Enzymes
04 Diabetes Mellitus |
|
| Description |
Aldose reductase, the first key enzyme in the polyol pathway, is involved in complications of diabetes. Sclerotiorin, isolated and purified from the fermented broth of Penicillium frequentans, inhibited aldose reductase with an IC(50 )0.4 microM. The inhibitor also showed antibacterial activity against Bacillus spp.
|
|
| Date |
2006
|
|
| Type |
Article
PeerReviewed |
|
| Format |
application/pdf
|
|
| Language |
en
|
|
| Identifier |
http://ir.cftri.com/1921/1/Sclerotiorin.pdf
Chidananda, C. and Jaganmohan Rao, L. and Sattur, A. P. (2006) Sclerotiorin from Penicillium frequentans, a potent inhibitor of aldose reductase. Biotechnology Letters, 28 (20). pp. 1633-1636. ISSN 0141-5492 |
|