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RuO4 catalyzed dihydroxylation for the synthesis of mixed medium-chain triacylglycerols.

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Relation http://ir.cftri.com/13809/
https://doi.org/10.1016/j.tetlet.2015.04.008
 
Title RuO4 catalyzed dihydroxylation for the synthesis of mixed
medium-chain triacylglycerols.
 
Creator Nandini, K.
Srinivas, P.
Bettadaiah, B. K.
 
Subject 17 Fatty Acid Chemistry
 
Description RuO4 catalyzed dihydroxylation of allyl acylates (C5 to C12) to glyceryl acylates is reported. The dihydroxylation was a major product (61–85%) with C5–C7 whereas carbonyl compounds by double bond fission were major with C8–C12 systems. 1-Hexanoylglycerol, obtained in high yields (85%), was further acylated with medium chain fatty acid chlorides to prepare mixed medium chain triglycerides (85–90%). Hence, a facile preparation of triacylglycerols such as C6–C6–C6, C6–C8–C8, C6–C10–C10, and C6–C12–C12 is accomplished.
 
Date 2015
 
Type Article
PeerReviewed
 
Format pdf
 
Language en
 
Identifier http://ir.cftri.com/13809/1/Tetrahedron%20Letters%20Volume%2056%20issue%2021%202015%20%5Bdoi%2010.1016%252Fj.tetlet.2015.04.008%5D%20Nandini%2C%20K.%3B%20Srinivas%2C%20P.%3B%20Bettadaiah%2C%20B.K.%20--%20RuO4%20catalyzed%20dihydroxylation%20for%20the%20synthesis%20of%20mixed%20medium-chain%20t.pdf
Nandini, K. and Srinivas, P. and Bettadaiah, B. K. (2015) RuO4 catalyzed dihydroxylation for the synthesis of mixed medium-chain triacylglycerols. Tetrahedron Letters, 56 (21). pp. 2704-2706.