ICAR Research Data Repository for Knowledge Management
Polymeric chitosan-glycolipid nanocarriers for an effective delivery of marine carotenoid fucoxanthin for induction of apoptosis in human colon cancer cells (Caco-2 cells).
IR@CSIR-CFTRI
View Archive Info| Field | Value | |
| Relation |
http://ir.cftri.com/13839/
https://dx.doi.org/10.1016/j.msec.2018.06.018 |
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| Title |
Polymeric chitosan-glycolipid nanocarriers for an effective delivery of marine carotenoid fucoxanthin for induction of apoptosis in human colon cancer cells (Caco-2 cells).
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| Creator |
Ravi, Hindupur.
Kurrey, N. K. Yuki, Manabe Tatsuya, Sugawara Baskaran, V. |
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| Subject |
14 Carotenoid Chemistry
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| Description |
Fucoxanthin (FUCO), a marine carotenoid is photo-, and thermo-labile and poorly bioavailable due to its lipophilicity. Hence, we developed a chitosan (CS) + glycolipid (GL) nanogels (NGs) to increase cellular uptake and anticancer efficacy of FUCO (10 μM) in human colon cells (Caco-2). Effect of FUCO loaded in NGs with/with no GL was studied in comparison with micellar FUCO. Results showed that the cell viability was lower (p
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| Date |
2018
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| Type |
Article
PeerReviewed |
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| Format |
pdf
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| Language |
en
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| Identifier |
http://ir.cftri.com/13839/1/Materials%20Science%20%26%20Engineering%20C.pdf
Ravi, Hindupur. and Kurrey, N. K. and Yuki, Manabe and Tatsuya, Sugawara and Baskaran, V. (2018) Polymeric chitosan-glycolipid nanocarriers for an effective delivery of marine carotenoid fucoxanthin for induction of apoptosis in human colon cancer cells (Caco-2 cells). Materials Science and Engineering: C, 91. pp. 785-795. |
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