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Antiaflatoxigenic and Antimicrobial Activities of Schiff Bases of 2‑Hydroxy-4-methoxybenzaldehyde, Cinnamaldehyde, and Similar Aldehydes.

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Relation http://ir.cftri.com/13942/
https://dx.doi.org/10.1021/acs.jafc.7b02576
 
Title Antiaflatoxigenic and Antimicrobial Activities of Schiff Bases of
2‑Hydroxy-4-methoxybenzaldehyde, Cinnamaldehyde, and Similar
Aldehydes.
 
Creator Nanishankar, V. Harohally
Chris, Cherita
Praveena, Bhatt
Anu Appaiah, K. A.
 
Subject 24 Organic Chemistry
15 Flavour/Fragrance/Perfumes
 
Description 2-Hydroxy-4-methoxybenzaldehyde (HMBA) is a nontoxic phenolic flavor from dietary source Decalipus
hamiltonii and Hemidesmus indicus. HMBA is an excellent antimicrobial agent with additional antiaflatoxigenic potency. On the
other hand, cinnamaldehyde from cinnamon is a widely employed flavor with significant antiaflatoxigenic activity. We have
attempted the enhancement of antiaflatoxigenic and antimicrobial properties of HMBA, cinnamaldehyde, and similar molecules
via Schiff base formation accomplished from condensation reaction with amino sugar (D-glucamine). HMBA derived Schiff bases
exhibited commendable antiaflatoxigenic activity at the concentration 0.1 mg/mL resulting in 9.6 ± 1.9% growth of Aspergillus
flavus and subsequent 91.4 ± 3.9% reduction of aflatoxin B1 with respect to control.
 
Date 2017
 
Type Article
PeerReviewed
 
Format pdf
 
Language en
 
Identifier http://ir.cftri.com/13942/1/J.%20Agric.%20Food%20Chem.%202017%2C%2065%2C%208773%E2%88%928778.pdf
Nanishankar, V. Harohally and Chris, Cherita and Praveena, Bhatt and Anu Appaiah, K. A. (2017) Antiaflatoxigenic and Antimicrobial Activities of Schiff Bases of 2‑Hydroxy-4-methoxybenzaldehyde, Cinnamaldehyde, and Similar Aldehydes. Journal of Agricultural and Food Chemistry, 65. pp. 8773-8778. ISSN 0021-8561