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Molecular characterization and histopathological studies on Fasciola gigantica in Mithun (Bos frontalis)

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Title Molecular characterization and histopathological studies on Fasciola gigantica in Mithun (Bos frontalis)
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Creator J.K. Chamuah*, D. Borkotoky, Amenti, K. Khate, S.S Jacob, Lalchamliani, O.K. Raina, M.H Khan and A. Mitra
 
Subject Fasciola gigantica, Mithun, Molecular identification, Pathological alteration.
 
Description Not Available
Mitochondrial DNA sequence of the sub-unit 1 of cytochrome c oxidase (Cox1) and ribosomal DNA sequence of the first
internal transcribed spacer (ITS-1) of Fasciola collected from mithun and cattle from Arunachal Pradesh, India were
characterized at molecular level in order to identify the species of parasite. Based on sequence and phylogenetic analysis,
the identity of the parasite was confirmed as Fasciola gigantica in mithun as well as from cattle. In order to know
histopathological alteration in Fasciola infection, a histopathological study was performed on eight liver specimens, out of
110 animals studied during the period from 2010-2016. Histopathological examination of F.gigantica infected liver showed
extensive fibrous connective tissue proliferation with necrosis of hepatocytes and infiltration of polymorphonuclear cell.
There was evidence of migratory tracts of parasites with losing of normal lobular hepatic architecture. Bile duct proliferation
was followed by congestion of portal vein with perivascular cuffing with surrounding degeneration of hepatocytes. The
hepatocytes showed pyknosis with hyperplasia of bile duct.
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Date 2019-11-11T05:19:51Z
2019-11-11T05:19:51Z
2017-10-07
 
Type Research Paper
 
Identifier Not Available
Not Available
http://krishi.icar.gov.in/jspui/handle/123456789/24640
 
Language English
 
Relation Not Available;
 
Publisher Not Available