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Protective Effect of Squalene against Isoproterenol-Induced Myocardial Infarction in Rats

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Title Protective Effect of Squalene against Isoproterenol-Induced Myocardial Infarction in Rats
Not Available
 
Creator Farvin, K. H. S.
Anandan, R.
Sankar, T. V.
Viswanathan Nair, P. G.
 
Subject squalene
isoproterenol
myocardial infraction
lipid peroxidation
mineral status
membrane-bound ATPases
 
Description Not Available
The protective effect of squalene on membrane function and mineral status was examined in isoproterenol-induced myocardial infarction in male albino rats. (ALT, AST, LDH and CPK). It counteracted isoproterenol-induced lipid peroxidation in plasma and heart tissue, and maintained the level of reduced glutathione in the heart tissue at near normalcy. Supplementation of squalene also exerted membrane stabilizing action against isoproterenol-induced myocardial infarction by maintaining the activities of membrane-bound ATPases (Na + , K + ATPase and Ca 2+ATPase) in heart tissue and the mineral status (sodium, potassium and calcium) in plasma and heart tissue at near normal levels.
Not Available
 
Date 2022-09-16T10:22:55Z
2022-09-16T10:22:55Z
2005
 
Type Research Paper
 
Identifier Farvin, K. H. S., Anandan, R., Sankar, T. V. and Viswanathan Nair, P. G.(2005) Protective Effect of Squalene against Isoproterenol-Induced Myocardial Infarction in Rats. Journal of Clinical Biochemistry and Nutrition. 37(2): 55-60.
0912-0009
http://krishi.icar.gov.in/jspui/handle/123456789/74273
 
Language English
 
Relation Not Available;
 
Publisher J Stage