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Antimicrobial activity of Agarwood oil against multiple-drug-resistant (MDR) microbes of clinical, food and environmental origin

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Title Antimicrobial activity of Agarwood oil against multiple-drug-resistant (MDR) microbes of clinical, food and environmental origin
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Creator Singh BR, Sinha DK, Vinodhkumar OR, Vadhana P, Bhardwaj M, Saraf A, Dubey S, Pawde AM, De UK, Gupta VK.
 
Subject Antimicrobial Activity of Agarwood Oil Against Multiple-Drug-Resistant (MDR) Microbes of Clinical, Food and Environmental Origin
 
Description Not Available
Background and Objectives: Multiple-Drug-Resistance (MDR) among bacteria is an imminent problem and alternative therapies are seen as a future abode. Agarwood Oil (AO) is described to possess antimicrobial activity besides many other medicinal utilities. This paper discusses the antimicrobial activity of AO on MDR and non-MDR strains of microbes of 69 genera isolated from clinical and non-clinical samples.

Methods and Results: In this study sensitivity of microbes was determined for conventional antimicrobials and AO using disc diffusion assay followed by determination of minimum inhibitory concentration (MIC) using agar well dilution assay. A total of 18.5% (522) strains were found sensitive to AO. Carbapenem resistant bacterial strains were more often (p, ≤0.01) resistant to antibiotics with 4.2 times more odds (99% CI, 2.99-5.90) of being MDR than carbapenem sensitive strains but no difference in their AO sensitivity was observed. However, MDR strains were more often (p, 2.56 mg/mL.

Conclusion: The study concluded that MDR and AO resistance had a similar trend and AO may not be seen as a good antimicrobial agent against MDR strains.
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Date 2023-06-14T05:16:58Z
2023-06-14T05:16:58Z
2020-01-01
 
Type Article
 
Identifier Not Available
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http://krishi.icar.gov.in/jspui/handle/123456789/78321
 
Language English
 
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Publisher Not Available