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http://krishi.icar.gov.in/jspui/handle/123456789/23030| Title: | Synthesis and characterization of Azadirachta indica constructed silver nanoparticles and their immunomodulatory activity in fish. |
| Other Titles: | Not Available |
| Authors: | Rather AM, Bhat IA, Sharma N, Gora A, Ahmad PG Sharma R |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | College of Fisheries, Shirgoan, Ratnagiri, Maharashtra ICAR::Central Institute of Fisheries Education |
| Published/ Complete Date: | 2016-01-01 |
| Project Code: | Not Available |
| Keywords: | silver nanoparticles neem, immunomodulator, antimicrobial agent |
| Publisher: | Not Available |
| Citation: | Rather AM, Bhat IA, Sharma N, Gora A, Ahmad PG and Sharma R (2016). Synthesis and characterization of Azadirachta indica constructed silver nanoparticles and their immunomodulatory activity in fish. Aquaculture Research: 1-13. |
| Series/Report no.: | Not Available; |
| Abstract/Description: | Green synthesis of nanoparticles by using different biological agents has emerged as an alternative to overcome the toxic effect of chemically synthesized nanoparticles. Among various biological agents, plants are mostly preferred. This study describes an eco-friendly and green synthesis of silver nanoparticles (G-AgNPs) using Azadirachta indica (neem) as a reducing agent. UV–Vis spectral analysis proved the wavelength of sample to be 420 nm, approaching the surface resonance peak specific for G-AgNPs. Dynamic light scattering (DLS) analysis showed the mean diameter of particles as 35.4 nm with zeta potential +34.6 mV. TEM results revealed the compact and spherical shape of the particles. Fourier transform infrared spectroscopies (FT-IR) demonstrate the presence of possible functional groups involved in synthesis of the silver nanoparticles. The functional activity of immunological parameters, such as nitroblue tetrazolium assay, myeloperoxidase activity, phagocytic activity, anti-protease and lysozyme activity, increased significantly (P < 0.05) in fish treated with G-AgNPs. Relative percentage survival (74%) and enhanced disease resistance were observed in G-AgNP-treated Cirrhinus mrigala fingerlings challenged with Aeromonas hydrophila. In summary, present results demonstrate biosynthesized silver nanoparticles have immunomodulatory and antibacterial activity. |
| Description: | Not Available |
| ISSN: | Not Available |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Aquaculture Research |
| NAAS Rating: | 7.75 |
| Volume No.: | 48 |
| Page Number: | 3742–3754 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | doi:10.1111/are.13199 |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/23030 |
| Appears in Collections: | FS-CIFRI-Publication |
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