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http://krishi.icar.gov.in/jspui/handle/123456789/38431| Title: | Supplementation of Betaine Attenuates HCl-Ethanol Induced Gastric Ulcer in Rats |
| Other Titles: | Not Available |
| Authors: | Ganesan, B. Yathavamoorthy, R. Farvin, K.S.H. Anandan, R. |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::Central Institute of Fisheries Technology |
| Published/ Complete Date: | 2010-03-31 |
| Project Code: | Not Available |
| Keywords: | Not Available |
| Publisher: | Science Alert |
| Citation: | Ganesan, B., Yathavamoorthi, R.,Farvin, K.S.H. and Anandan, R. (2010) Supplementation of Betaine Attenuates HCl-Ethanol Induced Gastric Ulcer in Rats. International Journal of Biological Chemistry, 4: 79-89. |
| Series/Report no.: | Not Available; |
| Abstract/Description: | The anti-ulcer effect of betaine was evaluated in rat model of HCl-ethanol induced gastric ulcer. Oral administration of HCl-ethanol caused a significant increase in the number of lesions in the gastric mucosa, volume of gastric juice, acidity and decreased activity of the pepsin. An increased level of lipid peroxidation and diminished tissue antioxidant system was also observed. Pre oral treatment with betaine counteracted all these changes induced by HCl-ethanol and maintained the rats at near normalcy. The gastro protective potential was further confirmed by histopathological studies of the gastric mucosa. The anti-ulcerogenic activity of betaine might be ascribable to its ability to neutralize the hydrochloride secreted into the stomach and/or to its free radical scavenging activity which protects the gastric mucosa against oxidative damage by decreasing lipid peroxidation and strengthening the mucosal barrier. |
| Description: | Not Available |
| ISSN: | 2152-2561 (Online) 1819-155x (Print) |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | International Journal of Biological Chemistry |
| Volume No.: | 4(2) |
| Page Number: | 79-89 |
| Name of the Division/Regional Station: | Biochemistry and Nutrition Division |
| Source, DOI or any other URL: | https://scialert.net/abstract/?doi=ijbc.2010.79.89 |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/38431 |
| Appears in Collections: | FS-CIFT-Publication |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Supplementation of Betaine Attenuates HCl-Ethanol.pdf | 574.24 kB | Adobe PDF | View/Open |
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