KRISHI
ICAR RESEARCH DATA REPOSITORY FOR KNOWLEDGE MANAGEMENT
(An Institutional Publication and Data Inventory Repository)
"Not Available": Please do not remove the default option "Not Available" for the fields where metadata information is not available
"1001-01-01": Date not available or not applicable for filling metadata infromation
"1001-01-01": Date not available or not applicable for filling metadata infromation
Please use this identifier to cite or link to this item:
http://krishi.icar.gov.in/jspui/handle/123456789/46042| Title: | Anti-ulcerogenic potential of anthocyanin-loaded chitosan nanoparticles against alcohol-HCl induced gastric ulcer in rats |
| Other Titles: | Not Available |
| Authors: | Sreerekha, P. R. Dara, P. K. Vijayan, D. K. Chatterjee, N.S. Mahadevan, R. Suseela Mathew Ravishankar, C.N. Anandan, R. |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::Central Institute of Fisheries Technology |
| Published/ Complete Date: | 2020-12-17 |
| Project Code: | Not Available |
| Keywords: | Anthocyanin nanoparticles encapsulation anti-ulcerogenic protective effect |
| Publisher: | Taylor and Francis Group |
| Citation: | Sreerekha, P. R, Dara, P. K., Vijayan, D. K., Chatterjee, N. S., Mahadevan, R., Suseela Mathew, Ravishankar, C. N. and Anandan, R. (2020) Anti-ulcerogenic potential of anthocyanin-loaded chitosan nanoparticles against alcohol-HCl induced gastric ulcer in rats. Nat. Prod. Res.,https://doi.org/10.1080/14786419.2020.1860041 |
| Series/Report no.: | Not Available; |
| Abstract/Description: | Chitosan is more prominent in food applications due to its versatile properties. Anthocyanins have gained much research attention due to their multifaceted role in preventing various lifestyle ailments. Encapsulated anthocyanin- loaded chitosan nanoparticles (ACNPs) were prepared by conventional ionotropic gelation method. In the present study, the gastro-protective effect of encapsulated ACNPs was evaluated against absolute ethanol-hydrochloric acid (HCl-Ethanol mixture) induced gastric ulcer in male Wistar rats. The histopathology and microscopic scoring of ulcer data of stomach tissue sections revealed that oral administration of encapsulated ACNPs group can alleviate inflammation of induced-gastric ulcer. Further, the expression of anti-inflammatory cytokines (Interleukin 4, IL-4) and suppression of pro-inflammatory cytokines (Interferon gamma, IFN-γ) confirm the cytoprotective effect of encapsulated ACNPs against HCl-Ethanol induced necrotic damage to mucosal membrane. The results of the present study indicate that the gastro protective action of encapsulated ACNPs ascribable to at least in parts to its anti-inflammatory property. |
| Description: | Not Available |
| ISSN: | 1478-6419 |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Natural Product Research |
| Journal Type: | International Journal |
| NAAS Rating: | 8.16 |
| Impact Factor: | 2.0 |
| Volume No.: | Not Available |
| Page Number: | Not Available |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | https://doi.org/10.1080/14786419.2020.1860041 |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/46042 |
| Appears in Collections: | FS-CIFT-Publication |
Files in This Item:
There are no files associated with this item.
Items in KRISHI are protected by copyright, with all rights reserved, unless otherwise indicated.