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http://krishi.icar.gov.in/jspui/handle/123456789/51108| Title: | Supplementation of squalene attenuates experimentally induced myocardial infarction in rats |
| Other Titles: | Not Available |
| Authors: | Farvin, K. H. S. Kumar, S. H. S. Anandan, R. Suseela Mathew Sankar, T. V. Viswanathan Nair, P. G. |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR::Central Institute of Fisheries Technology |
| Published/ Complete Date: | 2007 |
| Project Code: | Not Available |
| Keywords: | Squalene Isoprenaline Myocardial infarction Protein Glycoprotein components Lipid peroxidation |
| Publisher: | Elsevier |
| Citation: | Farvin, K. H. S., Kumar, S. H. S., Anandan, R., Suseela Mathew, Sankar, T. V. and Viswanathan Nair, P. G. (2007) Supplementation of squalene attenuates experimentally induced myocardial infraction in rats. Food Chem. 105(4): 1390-1395. |
| Series/Report no.: | Not Available; |
| Abstract/Description: | We have investigated the preventive effects of squalene against isoprenaline-induced myocardial infarction in male albino rats. Supplementation with squalene significantly prevented the isoprenaline-induced adverse changes in the levels of protein and glycoprotein components in plasma and heart tissue of experimental groups of rats. It exerted an antioxidant effect by inhibiting the isoprenaline-induced lipid peroxidation and by maintaining the level of non-enzymatic free radical-scavenger, reduced glutathione at near normalcy. Histopathological observations also confirmed the possible cardioprotective action of squalene by maintaining the normal architecture of the heart tissue. The results of the present investigation demonstrate that supplementation with squalene offers cardioprotection in experimental rats by its antioxidant and membrane- stabilizing properties. |
| Description: | Not Available |
| ISSN: | 0308-8146 |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Food Chemistry |
| Journal Type: | International Journal |
| NAAS Rating: | 12.31 |
| Impact Factor: | 6.31 |
| Volume No.: | 105(4) |
| Page Number: | 1390-1395 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | https://doi.org/10.1016/j.foodchem.2007.05.034 |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/51108 |
| Appears in Collections: | FS-CIFT-Publication |
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