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http://krishi.icar.gov.in/jspui/handle/123456789/72596
Title: | Computational Modelling of Tetraodon nigroviridis Melanocortin-1 Receptor (MC1R) Protein and Identification of Natural Compounds as Putative Modulators. |
Other Titles: | Not Available |
Authors: | Pandey Saumya and Shrinivas Jahageerdar*. |
ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
Author's Affiliated institute: | ICAR: Central Institute of Fisheries Education |
Published/ Complete Date: | 2020-05-21 |
Project Code: | Not Available |
Keywords: | BLAHtetrone, Docking, G-protein coupled receptor, Homology modeling, Virtual screening |
Publisher: | NISCAIR |
Citation: | Not Available |
Series/Report no.: | Not Available; |
Abstract/Description: | In ornamental fisheries, body ornamentation, including the body colour, is of great economic importance. Melanocortin-1 receptor (MC1R) gene is primarily responsible for pigmentation in the majority of the vertebrates, and its modulation will help to understand the pigmentation and external body coloration. The present study was aimed to predict the MC1R tertiary protein structure of Tetraodon nigroviridis through homology modelling and to identify putative modulators. The tertiary protein structure of the MC1R protein of T. nigroviridis was homology modelled and validated. BLAHtetrone with binding efficiency of -9.7 kcal/mol was identified as a putative modulator of the MC1R protein |
Description: | Not Available |
ISSN: | Not Available |
Type(s) of content: | Research Paper |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Journal. of Scientific & Industrial Research |
Journal Type: | International |
NAAS Rating: | 7.06 |
Impact Factor: | 1.056 |
Volume No.: | 79 |
Page Number: | 705-708 |
Name of the Division/Regional Station: | Not Available |
Source, DOI or any other URL: | Not Available |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/72596 |
Appears in Collections: | FS-CIFE-Publication |
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