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http://krishi.icar.gov.in/jspui/handle/123456789/73049
Title: | Monoclonal antibodies against foot-and-mouth disease virus RNA polymerase for detection of virus infection. |
Other Titles: | Not Available |
Authors: | Anand K, Subhasmita B, Mani S, Sreedharan K, Suresh B, Reddy GBM, Madhusudan H |
ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
Author's Affiliated institute: | ICAR: Central Institute of Fisheries Education |
Published/ Complete Date: | 2020-11-17 |
Project Code: | Not Available |
Keywords: | Monoclonal, antibodies, RNA, virus infection, FMD virus |
Publisher: | WILEY |
Citation: | Not Available |
Series/Report no.: | Not Available; |
Abstract/Description: | Foot-and-mouth disease (FMD) is a major viral disease in farm animals. In the present study, seven monoclonal antibodies (mAbs) were produced against the FMD virus (FMDV)-encoded RNA-dependent RNA polymerase (3D protein) and characterized. Screening of mAb reactivity against three overlapping fragments of the 3D protein expressed in Escherichia coli revealed that the binding sites of all the mAbs were confined to the N-terminal one-third of the 3D protein. A selected mAb was utilized for detecting FMDV in the infected cell culture and tissues obtained from FMDV-infected animals. |
Description: | Not Available |
ISSN: | Not Available |
Type(s) of content: | Research Paper |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Microbiology and Immunology |
Journal Type: | International |
NAAS Rating: | 7.96 |
Impact Factor: | 1.955 |
Volume No.: | 65 (2) |
Page Number: | 95-98 |
Name of the Division/Regional Station: | Not Available |
Source, DOI or any other URL: | Not Available |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/73049 |
Appears in Collections: | FS-CIFE-Publication |
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