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http://krishi.icar.gov.in/jspui/handle/123456789/73113| Title: | Bacterial Resistance to Antimicrobial Agents. |
| Other Titles: | Not Available |
| Authors: | Varela MF*, Jerusha S, Lekshmi M, Ojha M, Wenzel N, Sanford LM, Hernandez AJ, Parvathi A, Kumar SH |
| ICAR Data Use Licennce: | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf |
| Author's Affiliated institute: | ICAR: Central Institute of Fisheries Education |
| Published/ Complete Date: | 2021-05-11 |
| Project Code: | Not Available |
| Keywords: | bacteria; antimicrobial resistance; infection; pathogenesis; multidrug resistance |
| Publisher: | Not Available |
| Citation: | Not Available |
| Series/Report no.: | Not Available; |
| Abstract/Description: | Bacterial pathogens as causative agents of infection constitute an alarming concern in the public health sector. In particular, bacteria with resistance to multiple antimicrobial agents can confound chemotherapeutic efficacy towards infectious diseases. Multidrug-resistant bacteria harbor various molecular and cellular mechanisms for antimicrobial resistance. These antimicrobial resistance mechanisms include active antimicrobial efflux, reduced drug entry into cells of pathogens, enzymatic metabolism of antimicrobial agents to inactive products, biofilm formation, altered drug targets, and protection of antimicrobial targets. These microbial systems represent suitable focuses for investigation to establish the means for their circumvention and to reestablish therapeutic effectiveness. This review briefly summarizes the various antimicrobial resistance mechanisms that are harbored within infectious bacteria. |
| Description: | Not Available |
| ISSN: | Not Available |
| Type(s) of content: | Research Paper |
| Sponsors: | Not Available |
| Language: | English |
| Name of Journal: | Antibiotics |
| Journal Type: | International |
| NAAS Rating: | 9.89 |
| Impact Factor: | 3.89 |
| Volume No.: | 10 (5) |
| Page Number: | 593 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | Not Available |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/73113 |
| Appears in Collections: | FS-CIFE-Publication |
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