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http://krishi.icar.gov.in/jspui/handle/123456789/81579
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hiremath J | en_US |
dc.contributor.author | Hemadri D | en_US |
dc.contributor.author | Nayakavadi S | en_US |
dc.contributor.author | Chethan Kumar HB | en_US |
dc.contributor.author | Sathish Gowda CS | en_US |
dc.contributor.author | Sharma D | en_US |
dc.contributor.author | Ramamoorthy R | en_US |
dc.contributor.author | Mamatha SS | en_US |
dc.contributor.author | Patil SS | en_US |
dc.contributor.author | Ranjini RA | en_US |
dc.contributor.author | Jayamohanan TV | en_US |
dc.contributor.author | Swapna SA | en_US |
dc.contributor.author | Gulati BR | en_US |
dc.date.accessioned | 2024-03-05T17:18:26Z | - |
dc.date.available | 2024-03-05T17:18:26Z | - |
dc.date.issued | 2023-11-13 | - |
dc.identifier.citation | Hiremath, J., Hemadri, D., Nayakvadi, S., Kumar, C., Gowda, C.S.S., Sharma, D., Ramamoorthy, R., Mamatha, S.S., Patil, S., Ranjini, R.A. and Jayamohanan, T.V., (2023). Epidemiological investigation of ASF outbreaks in Kerala (India): detection, source tracing and economic implications. Veterinary Research Communications, 1-11. | en_US |
dc.identifier.issn | 15737446 | - |
dc.identifier.uri | http://krishi.icar.gov.in/jspui/handle/123456789/81579 | - |
dc.description | Not Available | en_US |
dc.description.abstract | This study investigates suspected African swine fever (ASF) outbreaks in two villages of Kannur district in Kerala, India, with the aim of identifying the causative agent and its genotype, the source of infection, and estimating the economic losses due to the outbreaks. Clinically, the disease was acute with high mortality, while gross pathology was characterized by widespread haemorrhages in various organs, especially the spleen, which was dark, enlarged and had friable cut surfaces with diffuse haemorrhages. Notably, histopathological examination revealed multifocal, diffuse haemorrhages in the splenic parenchyma and lymphoid depletion accompanied by lymphoid cell necrosis. The clinico-pathological observations were suggestive of ASF, which was confirmed by PCR. The source of outbreak was identified as swill and it was a likely point source infection as revealed by epidemic curve analysis. The phylogenetic analysis of p72 gene identified the ASFV in the current outbreak as genotype-II and IGR II variant consistent with ASFVs detected in India thus far. However, the sequence analysis of the Central Variable Region (CVR) of the B602L gene showed that the ASFVs circulating in Kerala (South India) formed a separate clade along with those found in Mizoram (North East India), while ASFVs circulating in Arunachal Pradesh and Assam states of India grouped in to different clade. This study represents the first investigation of ASF outbreak in South India, establishing the genetic relatedness of the ASFV circulating in this region with that in other parts of the country. The study also underscores the utility of the CVR of the B602L gene in genetically characterizing highly similar Genotype II ASFVs to understand the spread of ASF within the country. | en_US |
dc.description.sponsorship | Not Available | en_US |
dc.language.iso | English | en_US |
dc.publisher | Springer publishers | en_US |
dc.relation.ispartofseries | Not Available; | - |
dc.subject | African swine fever | en_US |
dc.subject | Genotype II | en_US |
dc.subject | IGRII variant | en_US |
dc.subject | India | en_US |
dc.subject | Outbreak investigation | en_US |
dc.title | Epidemiological investigation of ASF outbreaks in Kerala (India): detection, source tracing and economic implications | en_US |
dc.title.alternative | Not Available | en_US |
dc.type | Research Paper | en_US |
dc.publication.projectcode | Not Available | en_US |
dc.publication.journalname | Veterinary Research Communications | en_US |
dc.publication.volumeno | 2023 | en_US |
dc.publication.pagenumber | 1-11 | en_US |
dc.publication.divisionUnit | Not Available | en_US |
dc.publication.sourceUrl | DOI: 10.1007/s11259-023-10254-3 | en_US |
dc.publication.authorAffiliation | ICAR::National Institute of Veterinary Epidemiology and Disease Informatics | en_US |
dc.publication.authorAffiliation | Regional Disease Diagnostic Laboratory, Kannur, Kerala, India. | en_US |
dc.publication.authorAffiliation | District Veterinary Centre, Kannur, Kerala, India. | en_US |
dc.publication.authorAffiliation | Department of Animal Husbandry, State Institute for Animal Diseases, Palode, Kerala, India. | en_US |
dc.ICARdataUseLicence | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf | en_US |
dc.publication.journaltype | Included NAAS Journal List | en_US |
dc.publication.naasrating | 8.20 | en_US |
dc.publication.impactfactor | 2.20 | en_US |
Appears in Collections: | AS-NIVEDI-Publication |
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