Antibiotic Residues in Aquatic Foods and Their Methods of Detection

Abstract

Antibiotic residues are often found in the aquatic foods due to direct use in aquaculture or arising from pollution of waterbodies from nonpoint sources. Exposure to these antibiotic residues through aquatic food has far-reaching health implications, including the advent of antibiotic resistance microorganisms. Hence, it is important to screen for remnants of antimicrobial drugs in foods to establish regulatory control and help prevent public health emergencies. “Liquid chromatography-tandem mass spectrometry (LC-MS/MS)”- based estimation is the pivotal process for accurate quantitative estimation and confirmation of the rest of the drugs in food. This chapter provides an overview of antibiotic residue analysis in fish and fish products employing “LC-MS/MS.” A brief description of the principle of analysis using “LC-MS/MS” has been provided. Further, discussion is centered on the analysis of proscribed antimicrobials such as nitrofuran metabolites and chloramphenicol, and analysis of multiclass antibiotics in a multiresidue analysis approach.