KRISHI
ICAR RESEARCH DATA REPOSITORY FOR KNOWLEDGE MANAGEMENT
(An Institutional Publication and Data Inventory Repository)
"Not Available": Please do not remove the default option "Not Available" for the fields where metadata information is not available
"1001-01-01": Date not available or not applicable for filling metadata infromation
"1001-01-01": Date not available or not applicable for filling metadata infromation
Please use this identifier to cite or link to this item:
http://krishi.icar.gov.in/jspui/handle/123456789/4662| Title: | Mutagenic and genotoxic evaluation of medicinal plant Euphorbia royleana latex to freshwater fish Channa punctatus (Bloch). |
| Other Titles: | Not Available |
| Authors: | P. Singh A. Dabas R. Srivastava N. S. Nagpure A. Singh |
| Published/ Complete Date: | 2014-01 |
| Project Code: | Not Available |
| Keywords: | Channa punctatus euphoria royleana genotoxocity commet assay DNA damage micronucleus |
| Publisher: | ResearchGate |
| Citation: | SINGH, P., DABAS, A., SRIVASTAVA, R., Nagpure, N.S. and SINGH, A., 2014. MUTAGENIC AND GENOTOXIC EVALUATION OF MEDICINAL PLANT EUPHORBIA ROYLEANA LATEX To FRESHWATER FISH CHANNA PUNCTA TUS (BLOCH). International Journal of Pharma and Bio Sciences, 5(1), pp.217-228. |
| Series/Report no.: | Not Available; |
| Abstract/Description: | The aim of present study was to evaluate the mutagenicity and genotoxicity induced due to medicinal plant Euphorbia royleana crude latex in fresh water fish Channa punctatus using micronucleus and single cell gel electrophoresis (SCGE) assays. Two sub-lethal concentration of crude latex were calculated using 24 hrs LC50 value and the fish specimens were exposed to these concentrations in a static system. Erythrocytes were sampled at the intervals of 24, 48, 72 and 96 hrs at the rate of five fish per interval for assessment of micronucleus induction and SCGE assay. Significant effects (P<0.05) for both concentration and time of exposure were observed in treated fish. Highest level of micronuclei induction in erythrocytes and DNA damage in the SCGE was at 96 hrs of exposure at all concentrations of crude latex. This study further confirmed that the micronucleus and SCGE assays are useful to determine potential genotoxicity of herbal formulation and might be appropriate as part of monitoring program. |
| Description: | Not Available |
| ISSN: | 0975-6299 |
| Type(s) of content: | Research Paper |
| Sponsors: | University Grants Commission, New Delhi |
| Language: | English |
| Name of Journal: | International Journal of Pharma and Bio Sciences |
| Volume No.: | 5(1) |
| Page Number: | 217-228 |
| Name of the Division/Regional Station: | Not Available |
| Source, DOI or any other URL: | Not Available |
| URI: | http://krishi.icar.gov.in/jspui/handle/123456789/4662 |
| Appears in Collections: | FS-NBFGR-Publication |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| www.ijpbs.net_cms_php_upload_3077_pdf (1).pdf | 6.55 MB | Adobe PDF | View/Open |
Items in KRISHI are protected by copyright, with all rights reserved, unless otherwise indicated.