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http://krishi.icar.gov.in/jspui/handle/123456789/62382
Title: | Bioactivities of extracts from the marine sponge Halichondria panicea |
Other Titles: | Not Available |
Authors: | Purushottama,G B Venkateswaran,K Pani Prasad,K Nalini,P |
ICAR Data Use Licennce: | Not Available |
Author's Affiliated institute: | Not Available |
Published/ Complete Date: | 2009 |
Project Code: | Not Available |
Keywords: | toxins sponges |
Publisher: | Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP |
Citation: | Not Available |
Series/Report no.: | Not Available |
Abstract/Description: | In the present study, we screened the biological activity of extracts from the marine sponge Halichondria panicea collected in the Arabian Sea. Crude toxin was obtained by methanol, chloroform-methanol (2:1) and aqueous extraction. Subsequently, the protein concentration of each crude extract was determined. The impact of both sponge methanolic and aqueous extracts was found to increase activities of Na+-K+ ATP-ase and Mg++ ATP-ase. In the case of chloroform-methanol extract, higher concentrations increased acetylcholine esterase (AchE) activity. The methanolic and chloroform-methanol extracts exhibited hemolytic activity on chicken and human erythrocytes, whereas the aqueous extract failed to do so. Methanol and aqueous extracts produced an immunostimulating effect and all extracts revealed angiogenic activity. The aqueous extract yielded nine bands by SDS-PAGE on 12% gel. |
Description: | Not Available |
ISSN: | Not Available |
Type(s) of content: | Article |
Sponsors: | Not Available |
Language: | English |
Name of Journal: | Journal of Venomous Animals and Toxins including Tropical Diseases |
Volume No.: | 15 |
Page Number: | 444-459 |
Name of the Division/Regional Station: | Not Available |
Source, DOI or any other URL: | http://eprints.cmfri.org.in/6045/1/puru_paper.pdf |
URI: | http://krishi.icar.gov.in/jspui/handle/123456789/62382 |
Appears in Collections: | FS-CMFRI-Publication |
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