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Please use this identifier to cite or link to this item:
http://krishi.icar.gov.in/jspui/handle/123456789/62620
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chakraborty,Rekha D | - |
dc.contributor.author | Paulraj,R | - |
dc.contributor.author | Lipton,A P | - |
dc.contributor.author | Chakraborty,Kajal | - |
dc.date.accessioned | 2021-09-16T05:25:47Z | - |
dc.date.available | 2021-09-16T05:25:47Z | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | Not Available | - |
dc.identifier.issn | Not Available | - |
dc.identifier.uri | http://krishi.icar.gov.in/jspui/handle/123456789/62620 | - |
dc.description | Not Available | en_US |
dc.description.abstract | Two new guaiane sesquiterpene derivatives, guai-2-en-10a-ol (1) and guai-2-en-10a-methanol (2), were chromatographically purified as major constituents of the CHCl3/CH3OH (1:1, v/v) soluble fraction of Ulva fasciata. Acetylation of 2 furnished guai-2-en-10a-methyl methanoate (3) with acetyl group at C11 position. The structures of the compounds were elucidated using one and two-dimensional NMR and mass spectrometric analysis. Compounds 2 and 3 exhibited significant inhibition to the growth of Vibrio parahaemolyticus with minimum inhibitory concentrations of 25 and 35 mg/mL, respectively. The electronegative C10 acetyl group with high polarisability (7.02� 10�24 cm3) in 3 appeared to withdraw electron cloud from substituted cycloheptyl ring and (R)-3-methylcyclohept-1-ene moiety, thus acting as the nucleophilic center of the molecule resulting in high bioactivity. | en_US] |
dc.description.sponsorship | Not Available | - |
dc.language.iso | English | - |
dc.publisher | Elsevier | en_US |
dc.relation.ispartofseries | Not Available | - |
dc.subject | Ulva fasciata Delile | en_US |
dc.subject | Guaiane sesquiterpenoides | en_US |
dc.subject | Antibacterial activity | en_US |
dc.subject | Minimum inhibitory concentration | en_US |
dc.title | Guaiane sesquiterpenes from seaweed Ulva fasciata Delile and their antibacterial properties | en_US |
dc.title.alternative | Not Available | - |
dc.type | Article | en_US |
dc.publication.projectcode | Not Available | - |
dc.publication.journalname | European Journal of Medicinal Chemistry | - |
dc.publication.volumeno | 45 | - |
dc.publication.pagenumber | 2237-2244 | - |
dc.publication.divisionUnit | Not Available | - |
dc.publication.sourceUrl | http://eprints.cmfri.org.in/10778/1/European Journal of Medicinal Chemistry_45_2010_Kajal Chakraborty.pdf | - |
dc.publication.authorAffiliation | Not Available | - |
dc.ICARdataUseLicence | Not Available | en_US |
dc.publication.submitter | krishi.admin2@icar.gov.in | - |
Appears in Collections: | FS-CMFRI-Publication |
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