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Please use this identifier to cite or link to this item:
http://krishi.icar.gov.in/jspui/handle/123456789/77348
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Not Available | en_US |
dc.date.accessioned | 2023-05-16T03:58:01Z | - |
dc.date.available | 2023-05-16T03:58:01Z | - |
dc.date.issued | 2022-07-06 | - |
dc.identifier.citation | Not Available | en_US |
dc.identifier.issn | Not Available | - |
dc.identifier.uri | http://krishi.icar.gov.in/jspui/handle/123456789/77348 | - |
dc.description | Not Available | en_US |
dc.description.abstract | Expression of three growth-associated genes, IGF-I, IGF-II and IGF acid- labile subu-nit (IGFALS), was compared between highest and lowest growth performing fami-lies of Clarias magur being genetically selected for growth. Only IGF-II and IGFALS showed 3.50- and 2.10-fold differential expression, respectively, in RNASeq data of five pooled tissues, brain, liver, muscle, kidney and gonads. Relative expression profil-ing in brain, liver and muscle by qPCR showed 3.4-fold and 2.8-fold upregulation of IGF-II in muscle and liver, respectively, in higher performing family compared with the lower ones, while IGF-I was invariant and also the less expressed gene in all tis-sues. IGFALS expression was found to vary in accordance with IGF-II. Genotyping of one non-synonymous SNP (valine to isoleucine) identified in IGFALS revealed a sig-nificantly higher frequency of the isoleucine genotype in the high- performing group. Present study shows that in magur, IGF-Is significantly expressed not only in the liver but also in the muscle. Unlike other teleosts like cyprinids and cichlids where IGF-I has been reported to be the major component in the somatotropic axis, IGF-II is seen to be the major type in catfish, as also reported in Channel catfish, and is upregulated in high- growth individuals. | en_US |
dc.description.sponsorship | Not Available | en_US |
dc.language.iso | English | en_US |
dc.publisher | Wiley | en_US |
dc.relation.ispartofseries | Not Available; | - |
dc.subject | differentially expressed genes, growth-related genes, real-time PCR, single-nucleotide polymorphism, transcriptome | en_US |
dc.title | Studies on the Indian catfish Clarias magur reveal Insulin-Like Growth Factor II to be the major type and its upregulation in high-growth performing fish | en_US |
dc.title.alternative | Not Available | en_US |
dc.type | Journal | en_US |
dc.publication.projectcode | Not Available | en_US |
dc.publication.journalname | Aquaculture Research | en_US |
dc.publication.volumeno | 53(15) | en_US |
dc.publication.pagenumber | 5253-5260 | en_US |
dc.publication.divisionUnit | Not Available | en_US |
dc.publication.sourceUrl | Not Available | en_US |
dc.publication.authorAffiliation | Haldar C, Ram R, Pavan-Kumar A, Gireesh-Babu P, Koringa P, Joshi CG, Chaudhari A | en_US |
dc.ICARdataUseLicence | http://krishi.icar.gov.in/PDF/ICAR_Data_Use_Licence.pdf | en_US |
dc.publication.naasrating | 8.18 | en_US |
dc.publication.impactfactor | 2.184 | en_US |
Appears in Collections: | FS-CIFE-Publication |
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