Record Details

Simulation Experiments on Efficiencies of Gene Introgression by Backcrossing

OAR@ICRISAT

View Archive Info
 
 
Field Value
 
Relation http://oar.icrisat.org/5709/
http://dx.doi.org/10.2135/cropsci2002.5570
 
Title Simulation Experiments on Efficiencies of Gene Introgression by Backcrossing
 
Creator Ribaut , J M
Jiang, C
Hoisington, D A
 
Subject Genetics and Genomics
 
Description Designing a highly efficient backcross (BC) marker-assisted selection (MAS) experiment is not a straightforward exercise, efficiency being defined here as the ratio between the resources that need to be invested at each generation and the number of generations required to achieve the selection. This paper presents results of simulations conducted for different strategies, using the maize genome as a model, to compare allelic introgression with DNA markers through BCs. Simulation results indicate that the selection response in the BC1 could be increased significantly when the selectable population size (N sl) is 100. Selectable population size is defined as the number of individuals with favorable alleles at the target loci from which selection with markers can be carried out on the rest of the genome at nontarget loci, simulations considered the allelic introgression at one to five target loci, with different population sizes, changes in the recombination frequency between target loci and flanking markers, and different numbers of genotypes selected at each generation. For an introgression at one target locus in a partial line conversion, and using MAS at nontarget loci only at one generation, a selection at BC3 would be more efficient than a selection at BC1 or BC2, due to the increase over generations of the ratio of the standard deviation to the mean of the donor genome contribution. With selection only for the presence of a donor allele at one locus in BC1 and BC2, and MAS at BC3, lines with
 
Publisher Crop Science Society of America
 
Date 2002
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Rights —
 
Identifier http://oar.icrisat.org/5709/1/CropSci_42_557%E2%80%93565_2002.pdf
Ribaut , J M and Jiang, C and Hoisington, D A (2002) Simulation Experiments on Efficiencies of Gene Introgression by Backcrossing. Crop Science, 42 (2). pp. 557-565. ISSN 0011-183X