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Anticlastogenic potential of pigeonpea (Cajanus cajan (L.) Millsp.) in white mice (Mus musculus L.)

OAR@ICRISAT

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Relation http://oar.icrisat.org/9443/
http://www.greenfarming.in/?articles=anticlastogenic-potential-of-pigeonpea-cajanus-cajan-l-millsp-in-white-mice-mus-musculus-l
 
Title Anticlastogenic potential of pigeonpea (Cajanus cajan (L.) Millsp.) in white mice (Mus musculus L.)
 
Creator Sanchez, G C
Tanquilut, N C
Tanquilut, M R C
Soriano Junior, H R
Mula, M G
Mula, R P
 
Subject Pigeonpea
 
Description This study investigated the anticlastogenic potential of International Crop Research Institute for Semi-Arid Tropics (ICRISAT)
bred pigeonpea utilizing the micronudeus test using white mice models to determine the number of micronucleated
polychromatic erythrocytes (MPCEs) in treated and non-treated white mice at the Pampanga State Agricultural University
(PSAU), Magalang, Pampanga, Philippines. Furthermore, the study disclose if pigeonpea has detrimental effects on the vital
signs and some vital organs such as lungs, heart, liver, kidney and intestine. Based on the study, pigeonpea ICPL 87051
leaves decoction have anticlastogenic effects. This might be attributed to the presence of flavonoids, tannins and stilbenes in
pigeonpea leaves that has the ability to lower MPCEs in treated and non-treated white mice. In terms of its effects on the vital
signs namely heart rate, respiratory rate and temperature, results showed that pigeonpea did not cause heart palpitation,
tachycardia, hyperpnea and hypothermia. Treatments T+ (Positive control, TCN) and T2 (Pigeonpea leaves extract of 0.5 per
20 kg body weight + TCN) have normal heart, liver, kidney, lungs and intestines.
 
Publisher Green Farming
 
Date 2016
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Rights —
 
Identifier http://oar.icrisat.org/9443/1/Anticlastogenic%20potential%20of%20pigeonpea.pdf
Sanchez, G C and Tanquilut, N C and Tanquilut, M R C and Soriano Junior, H R and Mula, M G and Mula, R P (2016) Anticlastogenic potential of pigeonpea (Cajanus cajan (L.) Millsp.) in white mice (Mus musculus L.). Green Farming, 07 (02). pp. 357-360. ISSN 0974-0775