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Sesquiterpenoids with free-radical-scavenging properties from marine macroalga Ulva fasciata Delile

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Relation http://eprints.cmfri.org.in/10780/
 
Title Sesquiterpenoids with free-radical-scavenging properties from marine macroalga
Ulva fasciata Delile
 
Creator Chakraborty, Kajal
Paulraj, R
 
Subject Bioactive compounds
Biochemistry
Algae
 
Description Free-radical-scavenging activities of various solvent extracts of Ulva fasciata, a chlorophytan marine macroalga
with significance as a food ingredient, from the southwestern coast of the Indian peninsula, were
evaluated using in vitro tests, including 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,20-azino-bis(3-ethylbenzothiazoline-
6-sulfonate) (ABTS) scavenging assays. Ethyl acetate (EtOAc) extract of Ulva fasciata displayed
markedly stronger DPPH (89.8 ± 4.2%) and ABTS�+ scavenging (82.6 ± 3.7%) activities at 0.1 mg/ml
than dichloromethane and n-hexane extracts. Radical scavenging assay-guided chromatographic separation
of the EtOAc extract, using a step gradient of petroleum ether/EtOAc yielded five major sesquiterpenoids.
After 8 min of incubation the ABTS�+ scavenging activity of one of these sesquiterpenoids was
higher (71.4 ± 1.5%) than that of Trolox (44.1 ± 1.5%), and therefore may have potential as a natural antioxidant
in the food industry.
 
Publisher Elsevier
 
Date 2010
 
Type Article
PeerReviewed
 
Format text
 
Language en
 
Identifier http://eprints.cmfri.org.in/10780/1/Sesquiterpenoids_Food%20Chemistry_122_2010_Kajal.pdf
Chakraborty, Kajal and Paulraj, R (2010) Sesquiterpenoids with free-radical-scavenging properties from marine macroalga Ulva fasciata Delile. Food Chemistry, 122. pp. 31-41.