Record Details

Novel cantilever for biosensing applications

DSpace at IIT Bombay

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Title Novel cantilever for biosensing applications
 
Creator KARHADE, OG
CHILUVERU, SS
APTE, PR
 
Subject microcantilever
ribbed microcantilever
notched microcantilever
biomolecular assay
biosensor
transducer
mems
 
Description Chemomechanical actuation of a microcantilever beam induced by biomolecular binding such as DNA hybridization and antibody-antigren binding is an important principle useful in biosensing applications. As the magnitude of the forces involved is very small, increasing the sensitivity of the microcantilever beams involved is a priority. In this paper we are considering to achieve this by structural variation of the cantilevers. Merely decreasing the thickness of the microcantilever may improve the sensitivity, but it gives rise to the disadvantages of 'arching' and lesser reliability due to greater probability of defects during fabrication. We consider a 'ribbed' cantilever that eliminates the disadvantages while improving the sensitivity simultaneously. Simulations for validation have been performed using the finite element analysis software ANSYS 8.0. The simulations reveal that a ribbed microcantilever is almost as sensitive as a thin cantilever and has relatively very low arching effect. Simulations also reveal that higher the arching lower is the sensitivity.
 
Publisher SPIE-INT SOC OPTICAL ENGINEERING
 
Date 2011-10-24T01:26:52Z
2011-12-15T09:11:21Z
2011-10-24T01:26:52Z
2011-12-15T09:11:21Z
2005
 
Type Proceedings Paper
 
Identifier Microfluidics, BioMEMS, and Medical Microsystems III,5718,48-53
0-8194-5692-6
0277-786X
http://dx.doi.org/10.1117/12.589679
http://dspace.library.iitb.ac.in/xmlui/handle/10054/15294
http://hdl.handle.net/100/2017
 
Source Conference on Microfludics, BioMEMS, and Medical Microsystems III,San Jose, CA,JAN 24-26, 2005
 
Language English