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Metabolic diversity in bacterial degradation of aromatic compounds

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Title Metabolic diversity in bacterial degradation of aromatic compounds
 
Creator PHALE, PS
BASU, A
MAJHI, PD
DEVERYSHETTY, J
VAMSEE-KRISHNA, C
SHRIVASTAVA, R
 
Subject cell-surface hydrophobicity
carbon catabolite repression
pseudomonas-putida strain
mobile genetic elements
cyclic adenosine-3',5'-monophosphate levels
terephthalate 1,2-dioxygenase system
encoding naphthalene dioxygenase
burkholderia-xenovorans lb400
acinetobacter-lwoffii k24
ring-fission mechanism
 
Description Aromatic compounds pose a major threat to the environment, being mutagenic, carcinogenic, and recalcitrant. Microbes, however, have evolved the ability to utilize these highly reduced and recalcitrant compounds as a potential source of carbon and energy. Aerobic degradation of aromatics is initiated by oxidizing the aromatic ring, making them more susceptible to cleavage by ring-cleaving dioxygenases. A preponderance of aromatic degradation genes on plasmids, transposons, and integrative genetic elements ( and their shuffling through horizontal gene transfer) have lead to the evolution of novel aromatic degradative pathways. This enables the microorganisms to utilize a multitude of aromatics via common routes of degradation leading to metabolic diversity. In this review, we emphasize the exquisiteness and relevance of bacterial degradation of aromatics, interlinked degradative pathways, genetic and metabolic regulation, carbon source preference, and biosurfactant production. We have also explored the avenue of metagenomics, which opens doors to a plethora of uncultured and uncharted microbial genetics and metabolism that can be used effectively for bioremediation.
 
Publisher MARY ANN LIEBERT INC
 
Date 2011-10-13T22:59:10Z
2011-12-15T09:16:03Z
2011-10-13T22:59:10Z
2011-12-15T09:16:03Z
2007
 
Type Review
 
Identifier OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY,11(3)252-279
1536-2310
http://dx.doi.org/10.1089/omi.2007.0004
http://dspace.library.iitb.ac.in/xmlui/handle/10054/13871
http://hdl.handle.net/100/2970
 
Language en