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A retrospective on the design and synthesis of novel molecules through a strategic consideration of metathesis and suzuki-miyaura cross-coupling

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Title A retrospective on the design and synthesis of novel molecules through a strategic consideration of metathesis and suzuki-miyaura cross-coupling
 
Creator KOTHA, S
MANDAL, K
 
Subject cross-coupling
cross-metathesis
natural products
ring-closing metathesis
ring-closing metathesis
asymmetric total-synthesis
olefin metathesis
arylboronic acids
claisen rearrangement
catalytic metathesis
buflavine analogs
concave reagents
nakadomarin-a
efficient
 
Description In recent years, ruthenium-catalyzed metathesis and palladium-catalyzed Suzuki-Miyaura cross-coupling reactions have proven to be the most efficient tools for carbon-carbon bond formation in synthetic organic chemistry. This is mainly because of the stability and remarkable functional-group tolerance of these catalysts. Therefore, the strategic consideration of these two powerful reactions can eventually minimize the synthetic steps for the construction of complex target molecules. In this perspective we summarize the efforts of many research groups who have used the combination of these two powerful reactions (either together in concert or separated by a few multistep sequences) for the synthesis of supramolecular ligands, polyaromatic compounds, and complex natural products.
 
Publisher WILEY-V C H VERLAG GMBH
 
Date 2011-10-12T13:30:19Z
2011-12-15T09:16:09Z
2011-10-12T13:30:19Z
2011-12-15T09:16:09Z
2009
 
Type Review
 
Identifier CHEMISTRY-AN ASIAN JOURNAL,4(3)354-362
1861-4728
http://dx.doi.org/10.1002/asia.200800244
http://dspace.library.iitb.ac.in/xmlui/handle/10054/13784
http://hdl.handle.net/100/3022
 
Language en