A retrospective on the design and synthesis of novel molecules through a strategic consideration of metathesis and suzuki-miyaura cross-coupling
DSpace at IIT Bombay
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Title |
A retrospective on the design and synthesis of novel molecules through a strategic consideration of metathesis and suzuki-miyaura cross-coupling
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Creator |
KOTHA, S
MANDAL, K |
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Subject |
cross-coupling
cross-metathesis natural products ring-closing metathesis ring-closing metathesis asymmetric total-synthesis olefin metathesis arylboronic acids claisen rearrangement catalytic metathesis buflavine analogs concave reagents nakadomarin-a efficient |
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Description |
In recent years, ruthenium-catalyzed metathesis and palladium-catalyzed Suzuki-Miyaura cross-coupling reactions have proven to be the most efficient tools for carbon-carbon bond formation in synthetic organic chemistry. This is mainly because of the stability and remarkable functional-group tolerance of these catalysts. Therefore, the strategic consideration of these two powerful reactions can eventually minimize the synthetic steps for the construction of complex target molecules. In this perspective we summarize the efforts of many research groups who have used the combination of these two powerful reactions (either together in concert or separated by a few multistep sequences) for the synthesis of supramolecular ligands, polyaromatic compounds, and complex natural products.
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Publisher |
WILEY-V C H VERLAG GMBH
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Date |
2011-10-12T13:30:19Z
2011-12-15T09:16:09Z 2011-10-12T13:30:19Z 2011-12-15T09:16:09Z 2009 |
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Type |
Review
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Identifier |
CHEMISTRY-AN ASIAN JOURNAL,4(3)354-362
1861-4728 http://dx.doi.org/10.1002/asia.200800244 http://dspace.library.iitb.ac.in/xmlui/handle/10054/13784 http://hdl.handle.net/100/3022 |
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Language |
en
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