Record Details

Hybrid systems through natural product leads: an approach towards new molecular entities

DSpace at IIT Bombay

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Field Value
 
Title Hybrid systems through natural product leads: an approach towards new molecular entities
 
Creator MEHTA, G
SINGH, V
 
Subject biological evaluation
dna
acid
estramycins
inhibitors
enediynes
estradiol
discovery
strategy
library
 
Description Hybrid systems are constructs of different molecular entities, natural or unnatural, to generate functional molecules in which the characteristics of various components are modulated, amplified or give rise to entirely new properties. These hybrids can be designed from carefully selected components either through domain intergration of key structural/functional features or via straightforward covalent linkages. Some of the recently reported hybrid systems based on steroid, carbohydrate, C-60-fullerene platforms, amongst others, mainly crafted with the object of enhancement of the therapeutical spectrum, will be discussed.
 
Publisher ROYAL SOC CHEMISTRY
 
Date 2011-10-13T22:43:43Z
2011-12-15T09:16:16Z
2011-10-13T22:43:43Z
2011-12-15T09:16:16Z
2002
 
Type Review
 
Identifier CHEMICAL SOCIETY REVIEWS,31(6)324-334
0306-0012
http://dx.doi.org/10.1039/b204748a
http://dspace.library.iitb.ac.in/xmlui/handle/10054/13868
http://hdl.handle.net/100/3079
 
Language en