Long term hydrophilic coating on poly(dimethylsiloxane) substrates for microfluidic applications
DSpace at IIT Bombay
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Title |
Long term hydrophilic coating on poly(dimethylsiloxane) substrates for microfluidic applications
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Creator |
MAHESHWARI, N
KOTTANTHARAYIL, A KUMAR, M MUKHERJI, S |
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Subject |
capillary-electrophoresis
surface modification oxygen-plasma electrochemical detection biomedical applications pdms polydimethylsiloxane fabrication devices chip poly(dimethylsiloxane) (pdms) plasma oxidation polyethylenimine (pei) xps surface modification contact angle |
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Description |
Poly(dimethylsiloxane) (PDMS) has been used extensively for microfluidic components and as substrates for biological applications. Since the native nature of PDMS is hydrophobic it requires a functionalization step for use in conjunction with aqueous media. Commonly, oxygen plasma treatment is used for the formation of hydrophilic groups on the surface. However, the hydrophilic nature of these surfaces is short lived and the surfaces quickly revert back to their original hydrophobic state. In this work, branched-polyethylenimine (b-PEI) was used for long term modification of plasma treated PDMS surface. Contact angle, X-ray photoelectron spectroscopy (XPS) and Atomic force microscopy (AFM) were used for characterization of the modified surfaces and their stability with time was studied. The results obtained demonstrate that comparatively higher stability, hydrophilic, positively charged surfaces can be obtained after b-PEI treatment. These b-PEI treated PDMS surfaces can be used as fluidic channels for the separation of molecules as well as a substrate for the adherence of bio-molecules or biological cells. .
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Publisher |
ELSEVIER SCIENCE BV
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Date |
2011-07-25T15:53:32Z
2011-12-26T12:51:22Z 2011-12-27T05:34:49Z 2011-07-25T15:53:32Z 2011-12-26T12:51:22Z 2011-12-27T05:34:49Z 2010 |
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Type |
Article
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Identifier |
APPLIED SURFACE SCIENCE, 257(2), 451-457
0169-4332 http://dx.doi.org/10.1016/j.apsusc.2010.07.010 http://dspace.library.iitb.ac.in/xmlui/handle/10054/6725 http://hdl.handle.net/10054/6725 |
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Language |
en
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