Bacteriorhodopsin analogs from diphenylpolyene chromophores
DSpace at IIT Bombay
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Title |
Bacteriorhodopsin analogs from diphenylpolyene chromophores
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Creator |
SINGH, AK
MANJULA, D |
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Subject |
donor-acceptor diarylbutadienes
excited-state properties artificial bacteriorhodopsins fluorescence probe bovine rhodopsin pigment analogs purple membrane protein opsin alpha,omega-diphenylpolyenes |
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Description |
Chromophore-modified bacteriorhodopsin (bR) analogs are prepared, to study the nature of chromophore-protein interaction as well as to develop new bR analogs that can rind applications as photoactive element in molecular electronic devices. This article describes the preparation and characterization of hitherto unknown bR analogs based on diphenylpolyene chromophores. Diphenylpolyene compounds, namely, 4-[(E)-2-phenylvinyllbenzaldehyde (1), 3-methyl-5-14[(E)-2-phenylvinyllphenyl)penta-2E,4E-dienaI (2), 4-[4-phenylbuta-IE,3E-dienyllbenzaidehyde (3) and 3-methyl-5-14-[4phenylbuta-1E,3E-dienyllphenyllpenta-2E,4E-dienaI (4), have been synthesized, and their interaction with bacterioopsin (bOP) has been studied. Whereas aidehydes 2 and 4 interact with bOP and yield bR analogs bR-2 and bR-4, aldehydes 1 and 3 do not yield any pigment. Analogs bR-2 and bR-4 have been characterized for their opsin shift, competitive binding, photochemical properties and fluorescence spectral behavior.
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Publisher |
AMER SOC PHOTOBIOLOGY
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Date |
2011-07-17T06:49:47Z
2011-12-26T12:50:09Z 2011-12-27T05:36:12Z 2011-07-17T06:49:47Z 2011-12-26T12:50:09Z 2011-12-27T05:36:12Z 2003 |
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Type |
Article
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Identifier |
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 78(5), 503-510
0031-8655 http://dx.doi.org/10.1562/0031-8655(2003)078<0503:BAFDC>2.0.CO;2 http://dspace.library.iitb.ac.in/xmlui/handle/10054/4644 http://hdl.handle.net/10054/4644 |
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Language |
en
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