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MONOTERPENIC FRAGMENT ANALOGS OF APLASMOMYCIN AS POTENTIAL ANTIMALARIALS

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Title MONOTERPENIC FRAGMENT ANALOGS OF APLASMOMYCIN AS POTENTIAL ANTIMALARIALS
 
Creator BALU, N
THOMAS, JV
BHAT, SV
 
Subject qinghaosu artemisinin
 
Description Seven analogues of monoterpenic fragment of aplasmomycin were synthesized as targeted antimalarial agents. The potency of the compound 6 was comparable with the sesquiterpene lactone artemisinin and the antibiotic aplasmomycin in vivo against Plasmodium berghei yoelli.
 
Publisher AMER CHEMICAL SOC
 
Date 2011-07-14T13:17:31Z
2011-12-26T12:48:24Z
2011-12-27T05:36:26Z
2011-07-14T13:17:31Z
2011-12-26T12:48:24Z
2011-12-27T05:36:26Z
1991
 
Type Article
 
Identifier JOURNAL OF MEDICINAL CHEMISTRY, 34(9), 2821-2823
0022-2623
http://dx.doi.org/10.1021/jm00113a021
http://dspace.library.iitb.ac.in/xmlui/handle/10054/3963
http://hdl.handle.net/10054/3963
 
Language en